research Drug Repurposing: Hypothesis, Molecular Aspects, and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
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research Biochemistry of Epidermal Stem Cells
The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
research Targeted Therapy in Melanoma
New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.
research 6-Gingerol Inhibits Hair Shaft Growth in Cultured Human Hair Follicles and Modulates Hair Growth in Mice
6-Gingerol, found in ginger, may slow down hair growth and could be used for hair removal.
research Tumor Promotion in Skin: Are Active Oxygen Species Involved?
Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.
research Correction of Hair Shaft Defects Through Allele-Specific Silencing of Mutant Krt75
Using special RNA to target a mutant gene fixed hair problems in mice.
research The Cry of the Children: The Edwardian Medical Campaign Against Maternal Drinking
The Edwardian medical campaign linked maternal drinking to infant mortality and national decline, influencing hygiene education and leading to a ban on children under 14 from pubs.
research Introduction to Transplantology
The document concludes that transplantology has evolved with improved techniques and materials, making transplants more successful and expanding the types of transplants possible.
research Preparation of Anticancer Extract
Hibiscus micranthus leaf extract is safe and effective for antibacterial and wound healing.
research Association of Oxidative Stress in Mild Patchy Alopecia Areata: A Case-Control Study
Oxidative stress is linked to mild patchy alopecia areata.
research Stabilization of Epithelial Beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis
Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.
research Can You Diagnose Hair Loss (Non-Scarring Alopecia)
Non-scarring hair loss can be diagnosed with two 4mm punch biopsies, one cut vertically and the other transversely.
research Subungual Melanocytic Lesions: A Histopathological Review
Early subungual melanoma might be treated with less aggressive surgery because it invades the skin under the nail more slowly.
research Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development
Mitochondrial reactive oxygen species are essential for skin and hair development.
research How I Do It: Ahmad’s NPRT System: A New Classification System for Documenting Male Pattern Baldness
Dr. Muhammad Ahmad created a simpler system to better describe male pattern hair loss.
research How Biodegradable Polymers Can Be Effective Drug Delivery Systems for Cannabinoids: Perspectives and Challenges
Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.
research Retinoic Acid Drives Hair Follicle Stem Cell Activation via Wnt/Beta-Catenin Signalling in Androgenetic Alopecia
Retinoic acid helps activate hair growth in people with common hair loss by working on a specific cell growth pathway.
research The Role of Mutations on Gene AR in Androgenetic Alopecia Syndrome
Mutations in the AR gene cause hair thinning and loss.
research Wnt/β-Catenin Signaling: Function, Biological Mechanisms, and Therapeutic Opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research Actinic Keratosis: A Clinical and Epidemiological Review
Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.
research Metabolites From Macroalgae and Its Applications in the Cosmetic Industry: A Circular Economy Approach
Macroalgae compounds offer sustainable, effective benefits for cosmetics.
research Stabilization of Epithelial Beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis
Keeping β-catenin levels high in mammary cells disrupts their development and branching.
research Physiology and Medical Treatments for Alopecia
Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.
research Diagnosis and Management of Hair Loss in Children
Children's hair loss can be caused by various factors and should be treated with appropriate, age-specific methods and psychological support.
research Regeneration of Hair and Other Skin Appendages: A Microenvironment-Centric View
The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
research Do Changes in Chromosomes Cause Aging?
Chromosomal changes, including those in the WRN gene and rDNA, may significantly contribute to aging.
research Hair Physiology and Its Disorders
Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.
research Genomic and Phenotypic Characterization of Investigator Global Assessment (IGA) Scale-Based Endotypes in Atopic Dermatitis
Different types of atopic dermatitis were linked to specific genetic and immune changes, suggesting that severe cases might need stronger immune-targeting treatments.
research Managing Hair Loss in Midlife Women
The conclusion is that proper evaluation and treatment of hair loss in midlife women is important, considering the emotional impact and potential for various treatments.
research Acquired Progressive Kinking of the Hair in a Prepubertal Boy
A 10-year-old boy had the earliest reported case of hair that became progressively kinkier but eventually returned to normal on its own.