P4 Outcome Following Switch Between Brand Name And Generic Tacrolimus In Paediatric Population

January 2018 in “ Archives of Disease in Childhood ”

Peter Foxon, Swetha Vijayan

TLDR Switching to generic tacrolimus was safe, effective, and saved money.

The study evaluated the clinical outcomes of switching 36 paediatric patients from the brand name tacrolimus (Prograf) to its generic counterpart (Adoport) at Nottingham Children’s Renal Unit. The switch was monitored by reviewing Tacrolimus levels and clinical variations in immunosuppression before and after the switch. Results showed that most patients tolerated the switch well, with stable Tacrolimus levels and no significant changes in creatinine levels. Only one patient experienced hair loss and requested to revert to Prograf, and one patient required a dose adjustment. The switch resulted in cost savings for NHS England, supporting the use of Adoport as a cost-effective alternative to Prograf.

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community Help! Minoxidil or Duta to avoid Shed of long hair.

in Female 6 upvotes 2 months ago

The user is considering using Tacrolimus Solution and topical Dutasteride to avoid shedding caused by Minoxidil, which they fear may lead to facial side effects. They are also concerned about scalp sensitivity and are exploring different treatment bases to manage seborrheic dermatitis.

community Scalp Sunburns cause permanent hair loss. UPF hats protect you. Watch if you use Tretinoin on the scalp

in Technology 3 months ago

Sunburns on the scalp can cause permanent hair loss, especially for those using Tretinoin or Tacrolimus. Wearing UPF 50+ hats is recommended to protect against UV radiation.

community Scalp Sunburns can cause permanent hair loss. UPF hats protect you.

in Technology 3 months ago

Scalp sunburns can cause permanent hair loss, so wearing UPF hats is essential. Tretinoin and Tacrolimus users should be cautious of increased photosensitivity and potential scalp issues.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 65 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community RT1640 - Gray Hair Reversal Recipe

in Research/Science 3 upvotes 2 years ago

The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.

community If you could get for Christmas your own personalised topical anti hair loss serum that has the best the current science can offer, what would it contain and at what concentration?

in Treatment 1 upvotes 1 day ago

A personalized topical anti-hair loss serum could include high-dose setipiprant, high-dose CB 03-01, low-dose finasteride, minoxidil, latanoprost, and tretinoin. These ingredients are suggested for their potential effectiveness in promoting hair growth.

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