research Liposomes in Dermatology Today
Liposomes improve drug delivery and reduce skin irritation in dermatology.
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research Surrogate End-Points or Primary Outcomes in Clinical Trials in Women with Polycystic Ovary Syndrome?
The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
research Male Androgenetic Alopecia
DHT, a testosterone byproduct, causes male pattern baldness.
research Environmental Factors and Puberty Timing: Expert Panel Research Needs
Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.
research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Healthcare Innovation and Patent Law’s Pharmaceutical Privilege: Is There a Pharmaceutical Privilege? And If So, Should We Remove It?
The document suggests reevaluating the patent system to ensure public benefits from pharmaceutical privileges and to encourage more significant innovations.
research Polycystic Ovary Syndrome: Comprehensive Management and Health Impacts
PCOS is a common hormonal disorder in women that can lead to various health issues and requires comprehensive management.
research A Proprietary Herbal Extract Against Hair Loss in Androgenetic Alopecia and Telogen Effluvium: A Placebo-Controlled, Single-Blind, Clinical-Instrumental Study
The herbal extract was found to effectively reduce and prevent hair loss without any side effects.
research Do Men's Faces Really Signal Heritable Immunocompetence?
Masculine facial features may not reliably indicate heritable health, and more research is needed.
research Androgen- and Estrogen-Secreting Adrenal Cancers
Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.
research Hair Loss Diagnosis and Treatment Knowledge-Based System
Hair loss causes emotional distress, leading to high spending on treatments, with Minoxidil and Propecia being common but having side effects.
research How to Distinguish Medicalization from Over-Medicalization?
The article suggests using four questions to tell apart necessary medicalization from excessive medicalization, focusing on problem significance, social expectations, medical understanding, and effective resolution.
research Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13-Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation
The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.
research The Roles of Non-Coding RNA in the Development and Regeneration of Hair Follicles: Current Status and Further Perspectives
Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
research A Scientific Hypothesis on the Role of Nutritional Supplements for Effective Management of Hair Loss and Promoting Hair Regrowth
Nutritional supplements can help manage hair loss and promote hair growth by strengthening hair roots and countering harmful effects of pollution, smoking, and deficiencies in vitamins and minerals.
research Effects of the Level and Composition of Concentrate Supplements Before Breeding and in Early Gestation on Production of Different Hair Sheep Breeds
research Activation of Androgen Receptor Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
research An Updated Etiology of Hair Loss and the New Cosmeceutical Paradigm in Therapy: Clearing the Big Eight Strikes
New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
research New and Consolidated Therapeutic Options for Pubertal Induction in Hypogonadism: In-Depth Review of the Literature
There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.
research Intermittent Treatment with Farnesyltransferase Inhibitor and Sulforaphane Improves Cellular Homeostasis in Hutchinson-Gilford Progeria Fibroblasts
Alternating treatment with two drugs could help cells in a rapid aging disease.
research MicroRNA-21 in Skin Fibrosis: Potential for Diagnosis and Treatment
MicroRNA-21 could help diagnose and treat skin fibrosis.
research Premature Aging Syndromes: From Patients to Mechanism
Studying premature aging syndromes helps understand human aging and suggests potential treatments.
research The Acyl-CoA Binding Protein Is Required For Normal Epidermal Barrier Function In Mice
ACBP is crucial for healthy skin in mice.
research Southern African HIV Clinicians Society Gender-Affirming Healthcare Guideline for South Africa
The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.
research Combined Drug Triads for Synergistic Neuroprotection in Retinal Degeneration
Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
research Scaffold-Based Developmental Tissue Engineering Strategies for Ectodermal Organ Regeneration
Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.
research Hairless And The Polyamine Putrescine Form A Negative Regulatory Loop In The Epidermis
Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.
research Fibroblast State Switching Orchestrates Dermal Maturation and Wound Healing
Fibroblast state switching is crucial for skin healing and development.
research The Genetics of Hair Shaft Disorders
The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
research Clinical Features of Familial Lewy Body Parkinsonism Caused by α-Synuclein Triplication (Iowa Kindred) with Video Documentation
The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.