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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

People's decision-making can be influenced by their internal biological clocks, as shown by gene expression, not just self-reported preferences for morning or evening.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.

Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Four-amino acid part makes enzyme sensitive to finasteride.

The document suggests various treatments for PCOS, including medication for menstrual issues, insulin resistance, and excess hair, as well as fertility treatments, while highlighting the need for personalized care and lifestyle changes.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Advancements in hair biology include new treatments and tools for hair growth and alopecia.

The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

Testosterone is crucial for development, growth, and various body functions in mammals.

Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.

Fibrosing alopecia in a pattern distribution is a hair loss condition often confused with other types, requiring early treatment but usually not resulting in significant hair regrowth.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

DHT, a testosterone byproduct, causes male pattern baldness.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

The document suggests reevaluating the patent system to ensure public benefits from pharmaceutical privileges and to encourage more significant innovations.