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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

New genetic locations explain much of hair color variation in Europeans.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Finasteride and minoxidil work best together for hair loss.

FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

Current treatments for male pattern baldness include minoxidil and finasteride, with new options being developed.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

The document concludes that lifestyle changes and medical treatments can significantly reduce symptoms of Hidradenitis Suppurativa, a chronic skin condition.

Brothers of women with PCOS tend to have higher levels of a hormone called DHEAS, indicating a possible genetic link.

New gene identification techniques have improved the understanding and classification of inherited hair disorders.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

The document concludes that more research is needed to fully understand the causes of PCOS.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

New treatments for hair loss show promise, but more development is needed, especially for tough cases.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.

Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.

Hair aging is inevitable, but using the right hair care products can help maintain hair health.