January 2023 in “Indian Journal of Forensic and Community Medicine” This report describes two cases of thallium poisoning with gastrointestinal symptoms, peripheral neuropathy, and alopecia, which were effectively treated using activated charcoal, potassium chloride, and hemodialysis.
This case study reports on an 86-year-old woman with a rectal bezoar causing intermittent intestinal obstruction and bleeding, highlighting the importance of considering bezoars in gastrointestinal bleeding diagnosis and removal.
1 citations
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June 2023 in “Advances in therapy” In a real-world registry study, ripretinib showed effectiveness with a median progression-free survival of 7.70 months and a tolerable safety profile in Chinese patients using it as a fourth-line treatment for advanced GIST, particularly benefiting those with non-gastric tumors.
1 citations
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July 2017 in “PubMed” This study describes two Danish cases of Cronkhite-Canada syndrome presenting with malnutrition and gastrointestinal issues; both patients underwent successful treatment and remission after developing colonic adenocarcinomas.
December 2025 in “Asian Journal of Beauty and Cosmetology” In this study, researchers used gas chromatography–mass spectrometry to analyze agarwood from Laos and Thailand, identifying key volatile compounds also found in five other regions, and highlighted cytokine-regulated anti-inflammatory activity as a significant biological mechanism, suggesting potential for pharmaceutical and cosmetic applications.
August 2025 in “Frontiers in Nutrition” This study found that serum amino acid profiles changed significantly following laparoscopic sleeve gastrectomy in patients with obesity, and identified serum leucine levels as an independent risk factor for postoperative alopecia.
39 citations
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October 2014 in “Schweizerische medizinische Wochenschrift” This study found that while cyclophosphamide remains effective for severe autoimmune conditions, it is associated with gastrointestinal side effects, infections, some cases of irreversible amenorrhoea, and a higher risk of malignancies, emphasizing the need for long-term monitoring.
18 citations
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September 2003 in “International Journal of Cancer” This study found that Epstein-Barr virus infection upregulated a truncated variant of human basic hair keratin 1 (hHb1-ΔN) in gastric carcinoma cell lines, suggesting a possible link to carcinoma differentiation.
13 citations
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January 2013 in “Molecular genetics and metabolism” This study reported that mice on a phenylalanine-deficient diet showed symptoms such as weight loss, gastric dilation, and thymic depletion, which echo human phenylalanine deficiency manifestations.
8 citations
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November 2024 in “Journal of Neuroendocrinology” This review discusses the role of gut steroids in communicating with the gut microbiota and their potential implications in treating gastrointestinal disorders and related brain conditions, suggesting new perspectives on steroid molecules as therapeutic agents.
5 citations
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August 2018 in “Ocular immunology and inflammation” This study observed potential racial and gender differences in methotrexate side effects among uveitis patients, noting gastrointestinal issues were more common in males and Caucasians, while African Americans experienced more hair loss.
5 citations
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May 2006 in “Dermatologic Surgery” This study found that a PEEP of 10 mbar for 2 hours did not adversely affect liver function or gastric mucosal perfusion in patients after cardiac surgery, as long as cardiac output was maintained.
4 citations
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January 2017 in “Ciência Rural” This case report highlights that equine multisystemic eosinophilic epitheliotropic disease should be considered in horses presenting with skin lesions and gastrointestinal symptoms, as illustrated by the progression in a 5-year-old horse despite treatment.
This case report describes how unique endoscopic findings led to the diagnosis of Satoyoshi syndrome coexisting with systemic lupus erythematosus and gastric adenoma, expanding the endoscopic understanding of the syndrome.
March 2024 in “Revista Agraria Academica” This review reported that the dwarf palm (Chamaerops humilis) is traditionally used in North Africa for treating diabetes and gastrointestinal diseases, and identified a need for more research on its pharmacological and ethnobotanical properties, particularly in relation to its potential cancer-fighting uses.
January 2024 in “Current research in toxicology” This review reports that thallium poisoning causes severe neurological damage, with early gastrointestinal symptoms and later neurological dysfunction, and highlights the importance of early diagnosis and Prussian blue as an effective antidote.
This case report describes a 12-year-old male dog with hepatoid cell carcinoma, showing significant health improvement after a month of bioregulatory therapy, including gastroenteropathy resolution, hair regrowth, and restored vision.
140 citations
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December 2017 in “Journal of Controlled Release” This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.
58 citations
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April 2012 in “Journal of the American Academy of Dermatology” Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.
55 citations
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September 2017 in “Expert Opinion on Drug Discovery” This review examines the main absorption sites and influencing factors for orally administered drugs, highlighting variables such as solubility and gastrointestinal conditions that affect drug absorption in the small intestine and the development of effective drug delivery systems.
50 citations
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March 2021 in “Journal of investigational allergology & clinical immunology” This review examines existing research and clinical trials on the use of dupilumab for various skin, respiratory, and gastrointestinal disorders, but it reports no new clinical findings.
37 citations
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September 2017 in “Reumatología Clínica” In this systematic review and meta-analysis, methotrexate and leflunomide were compared for treating rheumatoid arthritis, showing similar efficacy overall. Methotrexate reduced swollen joints more effectively, while leflunomide was associated with fewer gastrointestinal side effects but more frequent liver enzyme increases.
35 citations
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October 2002 in “Biochemical and Biophysical Research Communications” This study reports that K7 expression patterns observed in mice are similar to those in humans, revealing previously unreported expression in the gastrointestinal tract, tongue, and various "hard" epithelial tissues.
25 citations
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July 2024 in “Frontiers in Pharmacology” Gepant medications for migraines show varied safety profiles in this study, with specific adverse events reported across systems like gastrointestinal and skin disorders, highlighting the need for tailored treatment and monitoring.
21 citations
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November 2017 in “Cochrane library” This study concluded that laparoscopic ovarian drilling does not clearly improve menstrual regularity or androgenic symptoms in PCOS compared to most medical treatments, but it may have fewer gastrointestinal side effects than metformin plus clomiphene.
17 citations
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March 2018 in “Pediatric dermatology” This study suggests that hydroxychloroquine may benefit some children with alopecia areata, as five out of nine patients showed improvement, although side effects like gastrointestinal intolerance and headache were noted.
16 citations
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May 2013 in “Australasian Journal of Dermatology” In this study, detailed examinations of alopecic lesions in two female Cronkhite-Canada syndrome patients suggested hair regrowth might occur without systemic corticosteroids if not required for gastrointestinal treatment, and hair loss may begin with anagen-telogen transition.
14 citations
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October 2003 in “Annals of Oncology” In this study, the researchers observed that the severity of capecitabine-induced hand-foot syndrome in advanced gastric cancer patients was not linked to the IVS14+1G→A mutation in the DPYD gene.
9 citations
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July 2022 in “Journal of Clinical Oncology” This study found that oral paclitaxel combined with encequidar improved tumor response rates compared to intravenous paclitaxel in women with metastatic breast cancer, while also reducing neuropathy but increasing certain gastrointestinal and neutropenic side effects.
9 citations
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September 2021 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This review examines the cutaneous manifestations of systemic diseases, including metabolic, cardiovascular, renal, gastrointestinal, and malignant conditions, as well as updates on skin signs of COVID-19, without presenting new study results.