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Topical minoxidil may not improve the appearance of balding men, according to a letter in this document.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Fat-related cells are important for initiating hair growth.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Low iron and L-lysine levels can cause hair loss in women, and increasing these nutrients can reduce hair shedding.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.