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Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.

New treatments for hair loss are showing promise due to better understanding of genetics and the immune system.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Ancient Chinese goats evolved cashmere-producing traits due to selective breeding, particularly in genes affecting hair growth.

A 14-year-old girl with severe hair loss regrew her hair using upadacitinib.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

STAT5 activation is crucial for starting the hair growth phase.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.