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Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.

Steroid hormones can help treat aging issues and improve health in elderly people.

Reproductive hormones play a crucial role in breast cancer development and treatment challenges.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

PCOS affects a similar percentage of Black and White women in the Southeastern United States.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

New alopecia treatments aim for better results and fewer side effects.

RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

Women with hyperandrogenic amenorrhea have similar bone density to healthy women but lower than androgenized women without amenorrhea, and high DHEAS levels might affect bone density.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Obese women had more testosterone and less acne, but similar hair growth compared to non-obese women.