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Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.

Using psychological treatments can help manage skin conditions along with regular medical care.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.

Cysteine helps maintain keratin production in skin cells even when iron is low.

Male skin gets drier and more alkaline as it ages, which may need different skincare than women's skin.

The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Claudin-1 is important for the barrier function and growth of hair.

Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Spironolactone might help protect against severe lung problems in COVID-19 patients.

A male with aromatase deficiency improved bone health with estradiol treatment.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.