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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Sebocytes play a key role in controlling androgen levels in human skin.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Use minoxidil for hair loss treatment; assess results after 6 months.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.

Minoxidil and finasteride effectively treat hair loss.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.