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research Clinical features and treatment outcomes of frontal fibrosing alopecia in men
FFA in men shows unique features and treatment results vary widely.
research Frontal fibrosing alopecia in association with Sjögren's syndrome: more than a simple coincidence
This review discusses the increasing reports of frontal fibrosing alopecia, a form of scarring alopecia, and its potential link to autoimmune disorders, but reports no new clinical results.
research A failure to relax.
This case study describes a 31-year-old man with myotonia and a history of hypertrophic cardiomyopathy and androgenic alopecia, who presented with arm and leg weakness.
research Frontal fibrosing alopecia: a retrospective clinical review of 62 patients with treatment outcome and long-term follow-up
This study found that early intervention and treatment with intralesional triamcinolone acetonide may stabilize hairline recession in patients with frontal fibrosing alopecia, although further research is needed for definitive treatment guidelines.
research Frontal fibrosing alopecia in males: A systematic review
This review discusses frontal fibrosing alopecia in males and reports no new clinical results, indicating a broader demographic affected by this inflammatory disorder beyond postmenopausal women.
research Aligning Stem Cell Models and Postmortem Studies to Query Striatal Neurodevelopment in Schizophrenia
In this study by Sawada et al., the researchers developed a human striatal model using stem cells and postmortem samples, revealing accelerated neuronal maturation and specific gene expression changes linked to schizophrenia risk, which may inform future research on the disorder's developmental roots.
research 253 Frontal fibrosing alopecia: clinical and therapeutic considerations - case series
In this case series, researchers reported on the clinical characteristics and treatment approaches for Frontal Fibrosing Alopecia in four cases, emphasizing the importance of early identification and intervention to manage this scarring hair loss disorder that primarily affects the frontal hairline and eyebrows.
research Frontal Fibrosing Alopecia and Increased Scalp Sweating: Is Neurogenic Inflammation the Common Link
This report discusses a series of patients with frontal fibrosing alopecia experiencing increased scalp sweating, which the authors hypothesize may be related to local skin inflammation affecting sweat gland activity.
research Tissue and Circulating MicroRNA Co-expression Analysis Shows Potential Involvement of miRNAs in the Pathobiology of Frontal Fibrosing Alopecia
This study identified four circulating microRNAs as highly predictive of frontal fibrosing alopecia status, suggesting potential roles in diagnostics and disease understanding.
research Post-finasteride syndrome - a true clinical entity?
research Possible Role of Osteopathic Manipulation Treatment in Alleviation of Finasteride-Induced Dementia through Modulation of HOMER-3 Gene Methylation
In this study, researchers found that finasteride induces dysregulation of genes related to neuropsychiatric disorders, including the HOMER-3 gene associated with dementia, and propose exploring craniosacral osteopathic therapy's potential to modulate this gene's methylation profile and alleviate related symptoms.
research Finasteride in Frontal Fibrosing Alopecia: Joining the Dots!
Finasteride may help treat frontal fibrosing alopecia, but more research is needed.
research TSPO ligand etifoxine attenuates LPS-induced cognitive dysfunction in mice
This study found that etifoxine pretreatment reduced neuroinflammation and improved cognitive function in LPS-induced neuroinflammation in mice, potentially through increased neurosteroid synthesis and reduced apoptosis.
research Sex hormones modulate pathogenic processes in experimental traumatic brain injury
This study found that pharmacological inhibition of sex steroid synthesis impacts pathogenic processes in traumatic brain injury in a sex-specific manner, with distinct effects of letrozole and finasteride on molecular and neurological outcomes.
research Formononetin: A Pathway to Protect Neurons
This review discusses the neuroprotective potential of formononetin, especially for neurological diseases, and reports no clinical results; the authors suggest its promise for developing central nervous system drugs.
research Frontal fibrosing alopecia: a disease that remains enigmatic
This review discusses the enigmatic nature of frontal fibrosing alopecia and reports no clinical results; the authors stress the need for further research.
research PSSD,PFS,PRSD: A perspective for aetiology and treatment
This paper introduces a framework attributing Post-SSRI, Post-Finasteride, Post-Retinoid, and an unnamed sexual dysfunction syndrome to downregulated estrogen receptor activity, potentially guiding future treatments in sexual medicine.
research [Striatal involvement on MRI in adrenomyeloneuropathy].
This case report describes a patient with adrenomyeloneuropathy, highlighting unusual MRI findings of high signal areas in the right striatum.
research Mitochondria Dysfunction and Inflammation in Traumatic Brain Injury: Androgens to the Battlefront
This review explores how androgen administration might help alleviate inflammation and mitochondrial impairment in traumatic brain injury but reports no new experimental findings, calling attention to the need for further investigation.
research Finasteride appears to be associated with an increased incidence of sexual dysfunction
research Synaptic Long-Term Potentiation and Depression in the Rat Medial Vestibular Nuclei Depend on Neural Activation of Estrogenic and Androgenic Signals
This study demonstrates that locally synthesized estrogen and androgen neurosteroids play opposite roles in long-term synaptic changes in male rats' medial vestibular nucleus, with testosterone-dihydrotestosterone mediating long-term depression and 17β-estradiol mediating long-term potentiation.
research Glabellar clinical and trichoscopic findings in patients with frontal fibrosing alopecia
In this case study, a 74-year-old patient with frontal fibrosing alopecia displayed unique trichoscopic and histopathological features, and treatments like 5-alpha reductase inhibitors and oral minoxidil effectively halted disease progression, highlighting the importance of comprehensive facial analysis for prognosis.
research Light therapy as a treatment for sexual dysfunction; focus on testosterone levels
research Congenital ptosis: Long-term outcome of frontalis suspension using autogenous temporal fascia or fascia lata in children
This study found that frontalis suspension surgery using autologous sling material effectively provided good to excellent long-term functional and aesthetic outcomes for children with severe congenital ptosis.
research Female sexual dysfunction in androgenetic alopecia: Case-control study
This study suggests that age, androgenetic alopecia, metabolic syndrome, and free testosterone levels may significantly affect sexual function in premenopausal women.
research Frontal Fibrosing Alopecia: An Update on Pathogenesis, Diagnosis, and Treatment
This review discusses the potential causes and treatments for frontal fibrosing alopecia but reports no new clinical findings, highlighting the need for further research to understand its pathogenesis and develop validated treatments.
research Frontal Fibrosing Alopecia and Reproductive Health: Assessing the Role of Sex Hormones in Disease Development
This narrative review suggests a strong association between abrupt hormonal imbalances and frontal fibrosing alopecia in women, especially related to reduced fertile years and certain hormonal therapies.
research Postmenopausal frontal fibrosing alopecia: A frontal variant of lichen planopilaris
This study reports that progressive frontal fibrosing alopecia, a distinct and gradually stabilizing form of lichen planopilaris affecting elderly women and often involving eyebrow hair loss, lacks effective treatments.
research Clinical features and sex hormone profile in male patients with frontal fibrosing alopecia: A multicenter retrospective study with 33 patients
Some overweight or obese men with long-term frontal fibrosing alopecia may have abnormal sex hormone levels.