29 citations
,
February 1989 in “Journal of Cutaneous Pathology” This case report identifies a new type of hair matrix tumor called "rippled pattern trichomatricoma," distinguished by its unique cell arrangement and differentiation features.
24 citations
,
January 2011 in “Sexual Development” This study observed that chemically-induced intersex frogs displayed altered brain mRNA profiles, with finasteride increasing certain hormone-related gene expressions and fadrozole reducing aromatase activity without affecting gene transcript levels.
94 citations
,
March 1996 in “Journal of Investigative Dermatology”
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that TSPyV T antigens can disrupt normal cell differentiation and proliferation in hair follicles and interfollicular epidermis, possibly contributing to trichodysplasia spinulosa pathology.
16 citations
,
January 2005 in “The International Journal of Developmental Biology” This study found that Hex gene expression patterns in chick embryo dorsal skin during feather bud development suggest a significant role in initiating feather morphogenesis.
38 citations
,
June 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” In this study, the RADA-PRG hydrogel enhanced SKP proliferation, survival, and gene expression, effectively supporting hair follicle regeneration in mice.
25 citations
,
July 2015 in “EMBO Reports” This study suggests that mouse lineage specification during pre-implantation development involves distinct timing and mechanisms for trophectoderm and inner cell mass differentiation, challenging existing models.
43 citations
,
August 2008 in “Regenerative Medicine” In this study, murine follicular cell aggregates developed into hair-like structures in culture, which upon implantation into mice skin matured into complete hair follicles, suggesting potential for treating hair loss.
45 citations
,
December 2007 in “The FASEB journal” This study demonstrated that hair follicle bulge stem cells can form epidermis in a tissue-engineered skin model, highlighting the significance of K5/K17 filaments in slow-cycling stem cell subsets.
42 citations
,
July 2015 in “PLoS ONE” This study presents the first detailed 3D models of the complete K1/K10 keratin dimer and identifies structural features and interactions that may inform understanding of keratin filament assembly.
October 2022 in “Regenerative Biomaterials” This study demonstrated that fibrin hydrogels support skin-derived precursors in hair follicle neogenesis in mice, with new hair growth and regeneration of blood vessels and sebaceous glands observed.
3 citations
,
January 1988 2 citations
,
June 2001 in “Medical Electron Microscopy” This study observed that the keratinization pattern of trichilemmal cysts in two Japanese women may originate from the proliferation of the outer root sheath in the follicular isthmus of anagen hairs.
July 2025 in “Journal of Investigative Dermatology” Secreted inhibitors of Wnt and IGF signaling control hair and tooth development, creating species-specific patterns.
30 citations
,
January 1999 in “Journal of Cutaneous Pathology” This study suggests that spiny keratoderma may be an ectopic hair formation on palms and soles, based on keratinization patterns observed using antikeratin antibodies and electron microscopy.
91 citations
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December 2000 in “The journal of cell biology/The Journal of cell biology” This study reports that expressed mouse type Ia and type IIa trichocyte keratins were successfully assembled into intermediate filaments in vitro, while also suggesting that disulfide bond cross linking enhances their stability.
29 citations
,
March 2012 in “Journal of Experimental Biology” This study found that ribbed hairs on tarantulas closely resemble chemoreceptors rather than silk-producing spigots, with no silk observed emitting from them under microscopy.
June 2023 in “Dermatopathology” In this case report, researchers described a unique skin lesion in a 55-year-old woman, identifying it as folliculosebaceous cystic hamartoma with an unusual combination of spindle cell lipomatous and neural components, which had not been previously documented in such cases.
7 citations
,
January 1990 in “Archives of Dermatological Research” Syringomas likely start in the upper dermis and form distinct luminal structures.
13 citations
,
December 1983 in “Canadian journal of zoology” This study found that mesenchymal cell processes from the dermal papilla contact epithelial hair matrix cells through gaps in the basal lamina during hair matrix cell differentiation in mouse vibrissa follicles.
5 citations
,
November 2024 in “Cells” This review highlighted that in an in vitro setting, 3D spheroid cultures of fish cells offer a promising alternative to traditional monolayer cultures, potentially advancing research in eco-toxicology, immunology, drug screening, and more by better mimicking in vivo conditions.
January 2012 in “Institutional Repositories DataBase (IRDB)” This study found that transplanting cell aggregates from mouse skin and lung mesenchymal cells can regenerate hair follicles in immunodeficient mice with skin wounds.
4 citations
,
August 1991 in “The Journal of Dermatology” This case report describes a rare pedunculated follicular hamartoma on the nasal septum of a 77-year-old Japanese male, emphasizing its unique clinical and pathological features.
1 citations
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May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers identified a temperature-sensitive mutation in the FERONIA gene of plants that prevents root hair formation at elevated temperatures, highlighting its role in maintaining root hair growth and response to plant hormones.
November 2024 in “The Journal of Cell Biology” This study revealed that basement membrane dynamics are crucial to hair follicle development, influencing progenitor cell behavior and cell division patterns in developing mouse hair follicles.
7 citations
,
January 2013 in “BioMed research international” This review highlights surprising similarities between hair follicles and antler units, suggesting that a comparative study of their biology could benefit understanding in both areas without presenting new empirical findings.
23 citations
,
January 2023 in “Journal of Developmental Biology” In this study, researchers discussed how specific protein interactions in reptile skin allow for the development of protective structures like scales and scutes, which facilitated reptiles' adaptation to terrestrial environments.
January 2026 in “PLoS Biology” This study used developing mouse hair follicles to explore early epithelial bud formation, finding that the Rho GTPase regulator ARHGEF3 plays a crucial role in regulating cell fate and cadherin patterning, with knockouts showing disrupted morphology and increased straight hair follicle growth.
13 citations
,
May 2017 in “Current Protocols in Stem Cell Biology” This study outlines a method to isolate hair follicle stem cells from mouse skin using fluorescence activated cell-sorting for use in research models, but reports no experimental findings.
3 citations
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March 2017 in “Pediatric Dermatology” This case report documents the first known instance of FOXN1 duplication linked to congenital hypertrichosis.