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A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Potential new drugs for treating PCOS were identified.

Neuropathic pruritus is a commonly overlooked and wrongly diagnosed type of chronic itching that is hard to treat.

Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.

Minoxidil helps lower high blood pressure in kids, but can cause fluid retention and hair growth.

Germ-free rats need biotin for growth and have different vitamin metabolism compared to regular rats.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Blood tests can detect ovarian Leydig cell tumors when scans don't, and surgery can confirm and treat these tumors.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Many elderly women experience unwanted facial hair and various hair loss conditions, with treatments available for each condition.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.

Chronic scalp pain in trichodynia involves both body-wide and localized increased pain sensitivity.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.

The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.

Hair transplant complications were likely due to deep graft placement and rough handling.

Hair cortisol may be a good indicator of recent mood in people with bipolar disorder.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Androgens can cause hair growth in some areas and hair loss on the scalp.

"Male-pattern" hair loss is common in women, especially after menopause, and doesn't always mean there's a problem with hormone balance.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.