November 2022 in “Journal of Investigative Dermatology” This study generated a transcriptomic map of human hair follicle compartments, providing a database for identifying compartment-specific gene expression which may aid in developing targeted treatments for hair follicle disorders.
May 2024 in “Journal of Cosmetic and Laser Therapy” This study found that three sessions of injectable platelet-rich fibrin (i-PRF+) significantly improved hair follicle density, hair volume, and thickness, as well as patient satisfaction in women with female pattern hair loss, with only minor self-limited adverse effects reported.
3 citations
,
January 2022 in “Journal of The American Academy of Dermatology” This study found that sunscreen and moisturizer use was associated with a higher likelihood of developing frontal fibrosing alopecia in the reviewed studies.
May 2007 in “Archives of Plastic Surgery” This study found that the Frechet flap technique provided aesthetically satisfactory outcomes for correcting the central slot defect created by scalp reduction surgery in the observed patients.
September 2024 in “Cutis” Sunscreen use may increase the risk of frontal fibrosing alopecia.
November 2025 in “Journal of Investigative Dermatology” This study found that the Arabidopsis thaliana protein Formin 2 localizes to plasmodesmata and is crucial for regulating their permeability by anchoring actin filaments, which affects virus susceptibility.
August 2026 in “ACTA MEDICA IRANICA” This study found that women with female pattern hair loss exhibited hormonal imbalances, with the Free Androgen Index being a particularly effective diagnostic marker.
1 citations
,
November 2023 in “Contact dermatitis” In this study, sensitization to ethylhexyl salicylate was found in 27.3% of patients with frontal fibrosing alopecia, suggesting it may be a potential contact allergen for this condition.
July 2022 in “Research Square (Research Square)” This study found that Egyptian women with frontal fibrosing alopecia had lower serum PPARγ levels and a higher occurrence of PPARG gene polymorphism compared to healthy controls, suggesting a potential role for PPARγ in the condition's development.
2 citations
,
January 2012 in “Journal of The Chilean Chemical Society” This study developed and validated a precise RP-HPLC-PDA method for estimating finasteride in bulk and tablet forms, suitable for quality control use.
1 citations
,
December 2019 in “Protetyka Stomatologiczna” This review discusses the use of platelet-rich fibrin in medical fields, especially dentistry, and reports no new clinical results.
7 citations
,
January 2019 in “PeerJ” This study found that intradermal injection of Secreted Frizzled-related Protein 4 inhibits, but does not block, hair follicle regeneration in mice, suggesting potential therapeutic applications for hair follicle regeneration disorders.
This study used molecular dynamics simulations to illustrate the complex molecular behavior of the hair surface F-layer, highlighting how fatty acids interact with 18-MEA under different conditions.
3 citations
,
February 2022 in “Dermatology practical & conceptual” This study found that trichoscopy is an effective noninvasive technique for diagnosing frontal fibrosing alopecia, confirming its valuable role alongside traditional histopathological examination.
17 citations
,
June 2016 in “Archives de Pédiatrie” This case report describes three pediatric cases of frontal fibrosing alopecia, a condition typically seen in postmenopausal women, including a unique instance involving female twins.
30 citations
,
June 2008 in “Dermatologic Surgery” In this study, the SAFE System for follicular unit extraction demonstrated a favorable average follicle transection rate of 6.14% and is accessible for physicians with basic technical skills, showing promise for wider adoption.
July 2023 in “Journal of Education, Health and Sport” This literature review reports that micro-needle radiofrequency is increasingly recognized in aesthetic medicine as a safe, effective treatment for various skin conditions, but further research is needed to optimize treatment parameters for the best outcomes.
April 2023 in “Journal of Investigative Dermatology” This study reports distinctive clinical, trichoscopic, and histopathological features of fibrosing alopecia in a pattern distribution among Chinese patients, suggesting possible racial differences compared to previous studies primarily involving Caucasians.
February 2026 in “Frontiers in Medicine” This study found that fibrosing alopecia in a pattern distribution in Hispanic male patients often resembles androgenetic alopecia, with a tendency for earlier onset compared to European and North American populations.
25 citations
,
January 2014 in “Annals of Dermatology” Sfrp2 increases during hair follicle catagen phase and slows keratinocyte growth.
8 citations
,
October 2016 in “Actas Dermo-Sifiliográficas” This study found that men with frontal fibrosing alopecia exhibited more frequent facial papules, androgenetic alopecia, and body hair loss compared to women with the condition, and were generally older.
1 citations
,
April 2024 in “Dermatology Practical & Conceptual” Hair loss in male frontal fibrosing alopecia may spare areas covered by a wristwatch.
27 citations
,
January 2006 in “Dermatologic Surgery” This study found that the SAFE System may improve follicular unit extraction by reducing follicle transection rates and broadening patient eligibility, with only minor adverse reactions reported.
1 citations
,
September 2021 in “The Journal of Dermatology” This study analyzed 24 Japanese cases of fibrosing alopecia in a pattern distribution and found a distinctive "parachute" hair loss pattern, emphasizing unique clinical characteristics potentially influenced by racial factors.
1 citations
,
December 2021 in “Development & Reproduction” This study found that FPR2 knockout mice experienced excessive hair loss and abnormal hair follicle structures, suggesting FPR2's protective role in hair regeneration through stem cell activity regulation.
January 2023 in “SSRN Electronic Journal” This study found that a fibroin-based cosmetic ingredient improved the mechanical properties and cuticle repair of African-American and Caucasian hair types, even when damaged by chemical treatments.
26 citations
,
June 2018 in “Australasian Journal of Dermatology” Stopping sunscreen use on the forehead led to hair regrowth in a woman with frontal fibrosing alopecia.
3 citations
,
May 2024 in “Indian Journal of Dermatology” In this case report, researchers identified a potential adverse skin reaction, called SDRIFE or Baboon syndrome, caused by the drug tofacitinib in a 19-year-old woman being treated for alopecia subtotalis, leading the authors to recommend discontinuation of the drug.
This study found that adding Platelet-Rich Plasma to Nanofat treatment for female pattern hair loss significantly increased terminal hair count and thickness after 6 months.