Clinical, Trichoscopic, and Histological Characteristics of 46 Hispanic Men With Fibrosing Alopecia in a Pattern Distribution: A Retrospective Multicenter Analysis

February 2026 in “ Frontiers in Medicine ”

Luis Enrique Sánchez-Dueñas, Irene Montserrat Rodriguez-Escamilla, Joel Alejandro Ramírez-Sánchez, Daniel Jimenez-Zaragoza, Guillermo Solis-Ledesma, Guillermo Antonio Guerrero-González, Miguel Marti-Machado, Mariana Lavia, Sonia S. Ocampo-Garza, Lizet K. Rojano-Fritz, Aldo Gálvez-Canseco, Leslie E. Rocha-Mendez, Nicole Orendain-Koch

fibrosing alopecia in a pattern distribution androgenetic alopecia Male Pattern of Hair Loss trichoscopic examination perifollicular desquamation histological analysis perifollicular lamellar fibrosis FAPD AGA MPHL

TLDR Fibrosing alopecia starts earlier in Latin American men and often looks like common male pattern baldness.

This study analyzed 46 Hispanic men with fibrosing alopecia in a pattern distribution (FAPD) across 8 dermatological centers in Argentina, Colombia, Mexico, and Peru. The mean age was 39, with onset ranging from 20 to 63 years. A significant 85% had a family history of androgenetic alopecia (AGA), and 65% exhibited Male Pattern of Hair Loss (MPHL). Trichoscopic examination revealed perifollicular desquamation in 96% of cases, while histological analysis showed concentric perifollicular lamellar fibrosis in all patients. FAPD was initially suspected in only 13% of cases, with AGA being the primary suspicion in 56.5%. The study concludes that FAPD onset is earlier in Latin American males compared to their European and North American counterparts, and most cases resemble AGA in hair loss patterns.

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