Clinical, Trichoscopic, and Histological Characteristics of 46 Hispanic Men With Fibrosing Alopecia in a Pattern Distribution: A Retrospective Multicenter Analysis

February 2026 in “ Frontiers in Medicine ”

Luis Enrique Sánchez-Dueñas, Irene Montserrat Rodriguez-Escamilla, Joel Alejandro Ramírez-Sánchez, Daniel Jimenez-Zaragoza, Guillermo Solis-Ledesma, Guillermo Antonio Guerrero-González, Miguel Marti-Machado, Mariana Lavia, Sonia S. Ocampo-Garza, Lizet K. Rojano-Fritz, Aldo Gálvez-Canseco, Leslie E. Rocha-Mendez, Nicole Orendain-Koch

fibrosing alopecia in a pattern distribution androgenetic alopecia Male Pattern of Hair Loss trichoscopic examination perifollicular desquamation histological analysis perifollicular lamellar fibrosis FAPD AGA MPHL

TLDR Fibrosing alopecia starts earlier in Latin American men and often looks like common male pattern baldness.

This study analyzed 46 Hispanic men with fibrosing alopecia in a pattern distribution (FAPD) across 8 dermatological centers in Argentina, Colombia, Mexico, and Peru. The mean age was 39, with onset ranging from 20 to 63 years. A significant 85% had a family history of androgenetic alopecia (AGA), and 65% exhibited Male Pattern of Hair Loss (MPHL). Trichoscopic examination revealed perifollicular desquamation in 96% of cases, while histological analysis showed concentric perifollicular lamellar fibrosis in all patients. FAPD was initially suspected in only 13% of cases, with AGA being the primary suspicion in 56.5%. The study concludes that FAPD onset is earlier in Latin American males compared to their European and North American counterparts, and most cases resemble AGA in hair loss patterns.

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Distinctive Age Distribution and Hair Loss Pattern Highlighting Uniqueness of Japanese Cases of Fibrosing Alopecia in a Pattern Distribution

research Distinctive Age Distribution and Hair Loss Pattern Highlighting Uniqueness of Japanese Cases of Fibrosing Alopecia in a Pattern Distribution

1 citations , September 2021 in “The Journal of Dermatology”

Japanese cases of fibrosing alopecia show a unique age and hair loss pattern, possibly due to racial differences.

Clinicopathological Characteristics and Treatment Outcomes of Fibrosing Alopecia in a Pattern Distribution: A Retrospective Cohort Study

research Clinicopathological Characteristics and Treatment Outcomes of Fibrosing Alopecia in a Pattern Distribution: A Retrospective Cohort Study

7 citations , August 2021 in “Journal of the European Academy of Dermatology and Venereology”

Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.

research Fibrosing Alopecia in a Pattern Distribution

30 citations , January 2020 in “Journal of The American Academy of Dermatology”

Fibrosing alopecia in a pattern distribution is a hair loss condition often confused with other types, requiring early treatment but usually not resulting in significant hair regrowth.

research Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study

56 citations , January 2019 in “Skin appendage disorders”

The most common hair loss type at specialist clinics is androgenetic alopecia, especially in younger men, followed by alopecia areata and telogen effluvium, with differences seen across regions.

research Clinical Study of Fibrosing Alopecia in a Pattern Distribution in a Latin American Population

13 citations , January 2018 in “International Journal of Dermatology”

The study found that treatment improved hair condition in patients with Fibrosing Alopecia in a Pattern Distribution in Chile.

research Fibrosing Alopecia in a Pattern Distribution

158 citations , February 2000 in “Archives of dermatology”

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

Semantic ratio: 80%