21 citations
,
October 1988 in “Clinics in Dermatology” This study found that topical minoxidil induced hair regrowth in stumptailed macaques, with more significant effects observed in younger animals, while cessation led to renewed balding and retreatment restored regrowth.
1 citations
,
October 2022 in “International Journal of Environmental Research and Public Health” This study found that Type 2 Diabetes was associated with a higher likelihood of Demodex folliculorum infestation in patients at a hospital in Peru.
May 2022 in “Journal of the Egyptian Society of Parasitology” This study found that Demodex folliculorum mites were detected in 1.6% of acne patients, with a higher prevalence in adolescents and those with severe acne.
March 2022 in “Journal of health sciences and medicine” This study found that azelaic acid at all tested concentrations showed anti-Demodex efficacy similar to 5% permethrin, with no statistically significant differences between the treatments.
January 1996 in “대한피부과학회지” This study found a significantly higher density of Demodex mites in sebaceous hyperplasia lesions compared to controls, suggesting a possible link between Demodex and the development of these skin lesions.
46 citations
,
May 1986 in “Seminars in Reproductive Medicine” Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.
34 citations
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December 1991 in “Annals of the New York Academy of Sciences” The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.
23 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that topical minoxidil and diazoxide induced significant hair regrowth in bald macaques, while a steroid 5 alpha-reductase inhibitor prevented baldness in preadolescent macaques.
1 citations
,
January 1997 in “Journal of Investigative Dermatology” In this study using a macaque model, RU58841 at a 5% concentration significantly increased hair density, thickness, and length in the frontal bald scalp over six months.
466 citations
,
August 2004 in “Journal of the American Academy of Dermatology” This article reviews the current literature on rosacea, focusing on the new subtype classification system and the main theories of its pathogenesis, but reports no new clinical results.
172 citations
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December 2004 in “Journal of The American Academy of Dermatology” In this study, demodicoses were found to be relatively common among immunocompetent patients, with a notable overlap with papulopustular rosacea.
149 citations
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March 1981 in “American Journal of Ophthalmology” This study found that Demodex folliculorum and Demodex brevis mites can cause eyelid follicular and glandular changes, potentially contributing to ocular disease in humans.
46 citations
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January 1988 in “PubMed” This study found that Demodex mites may transport Microsporum canis spores on human skin, suggesting a potential role in microbial movement despite typically being considered harmless.
35 citations
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March 1976 in “British Journal of Dermatology” This study observed no correlation between Demodex species and skin condition among Aborigines, though D. brevis was associated with sebaceous gland degeneration in one case.
30 citations
,
June 2013 in “Optometry and vision science” This study reports that a clinical sequence can help eye care practitioners identify Demodex mites, which are often underdiagnosed and undertreated in ocular surface diseases.
11 citations
,
June 2024 in “Clinical ophthalmology” This study highlights that Demodex mites, commonly found on human skin, can cause significant eye and skin issues such as blepharitis, rosacea, and dermatitis when present in abnormally high densities, underscoring the need for targeted management strategies.
9 citations
,
April 1987 in “International Journal of Dermatology” This article reviews rosacea and rosacea-like demodicidosis, discussing historical findings, but provides no new clinical results; the authors highlight the role of Demodex in related skin conditions.
4 citations
,
January 2021 in “Dermatology Review” This review discusses the role of Demodex mites in ocular demodecosis and various eye ailments, highlighting diagnostic methods but noting a lack of standardized treatments, with no new clinical results reported.
1 citations
,
September 2019 in “Pomeranian Journal of Life Sciences” This study found that Demodex infestation was present in 21% of healthy volunteers, with higher rates in older individuals and more common in PUM personnel than students.
1 citations
,
December 2011 in “Ophthalmology” This article comments on Nemet et al.'s study of blepharitis, emphasizing that Demodex folliculorum is a significant factor in its associated morbidity and can be effectively managed with tea tree oil shampoo.
August 2026 in “Dermatology and Therapy” In this review, researchers outline the characteristics of scalp rosacea, an underrecognized inflammatory dermatosis, describing its multifactorial pathogenesis, diagnostic features, and management strategies, noting its clinical similarities with facial rosacea and the absence of standardized diagnostic criteria or therapeutic guidelines.
November 2021 in “Transplantation direct” This case report highlights that Demodex folliculitis in an immunocompromised patient can result in severe and widespread eruptions, which were effectively treated with oral ivermectin and topical permethrin.
January 2020 in “International journal of medical parasitology and epidemiology sciences” This case report suggests that Demodex infection should be considered in patients with facial scaling and itching, as observed in a 36-year-old woman in Tabriz testing positive for the mites.
September 2025 in “Meditsinskiy sovet = Medical Council” This review provides current insights into the role of Demodex mites in acne and rosacea, detailing their involvement in sebaceous gland diseases due to their potential to cause inflammation and disrupt skin microbial balance, while suggesting methods to correct mite overgrowth.
March 2022 in “Egyptian Academic Journal of Biological Sciences. E, Medical Entomology and Parasitology” This review examines the potential pathogenicity of Demodex mites in skin disorders, considering systemic factors like immunological imbalance and microbiome changes, but reports no new clinical findings.
4 citations
,
January 2019 in “Skin appendage disorders” This study found that Follicular Maps, derived from trichoscopic images, remained consistent over time and unaffected by hair cycling or noncicatricial alopecia, offering a precise tool for diagnosing and monitoring hair and scalp conditions.
May 2017 in “InTech eBooks” This article describes various hair and scalp examination techniques, including noninvasive, semi-invasive, and invasive methods, noting that trichoscopy is a simple, well-accepted, noninvasive technique for evaluating hair loss patients and monitoring treatment.
1 citations
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May 2016 in “Dermatologic Surgery” The document concludes that using a phototrichogram with a protractor and tapeline is a reliable and noninvasive way to measure hair loss.
January 2026 in “Skin Appendage Disorders” This study concluded that including intermediate hairs or using relative shaft diameter methods can significantly improve the sensitivity of trichograms in diagnosing female androgenetic alopecia, aligning better with histopathology results.
45 citations
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January 2012 in “International Journal of Trichology” This study reported that trichoscopy is a more effective diagnostic tool than the trichogram for early diagnosis of FAGA, regardless of hair shaft diversity cut-off levels.