8 citations
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February 2016 in “The American Journal of Dermatopathology” In this study, the researchers found that transplanted hair follicles undergo significant morphological changes, including a thickened dermal sheath and increased hair shaft diameter, which are associated with altered follicular vascularization.
3 citations
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January 2023 in “Materials horizons” This study developed 3D micropatterns with magnesium silicate nanospheres that mimic vessels and hair follicles for potential use in skin regeneration by reconstructing vasculature and promoting hair growth.
December 2015 in “Vascular Pharmacology” Hair papilla cells are crucial for blood vessel development in hair follicles, affecting hair growth and loss.
In this study, personalized PRP therapy significantly increased hair density and diameter in a patient with androgenetic alopecia, highlighting its potential benefit but emphasizing the need for broader clinical trials.
1 citations
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July 2024 in “Australasian Journal of Ultrasound in Medicine” In this study, researchers reported that cutaneous ultrasound may be a valuable tool in diagnosing and assessing inflammatory activity in tinea capitis, potentially guiding treatment decisions, especially in severe cases not apparent through clinical symptoms alone.
January 2026 in “Cirugía Plástica .” This study reviewed preclinical evidence suggesting that topical glutamic acid can enhance hair regrowth and skin healing in burn-induced alopecia, highlighting its potential as a simple, low-cost treatment option that warrants further clinical trials.
58 citations
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January 2020 in “International Journal of Molecular Sciences” This review evaluates various kits for isolating platelet-rich plasma using established processing standards and finds they enable compliance with consensus quality criteria; ongoing research is needed to refine these procedures for improved consistency and safety.
3 citations
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August 2025 in “Stem Cell Research & Therapy” This review examines adipose-derived stem cells as a promising therapy for alopecia but reports no new clinical results, discussing their potential mechanisms and the challenges faced in treatment development.
This study suggests that bio-nanovesicles, such as exosomes and microvesicles, may enhance skin and hair follicle regeneration by modulating key signaling pathways, potentially overcoming the limitations of conventional treatments for alopecia and chronic skin diseases.
September 2025 in “Current Issues in Molecular Biology” This study highlights IGF-1's role in promoting hair follicle proliferation, vascularization, and growth, suggesting its potential as a treatment target for hair loss disorders like androgenetic alopecia, though more research on delivery methods and long-term effects is needed.
May 2025 in “Dermatology Reports” This report describes a successful case where repeated autologous lipostructure followed by hair transplantation improved scarring alopecia in a patient with morphea en coup de sabre, suggesting potential benefits from this combined approach.
December 2017 in “Facial plastic surgery” In this review, the authors discuss how advanced hair transplantation techniques can improve the aesthetic outcome of facial trauma involving hair-bearing areas, emphasizing the role of adjuvant therapies like fat transfer and platelet-rich plasma to enhance hair regrowth.
January 2026 in “International Society of Hair Restoration Surgery” In this case study, a 35-year-old male with severe burn-related scalp injuries underwent successful reconstruction through tissue expansion, skin grafts, and multiple hair transplant sessions, resulting in satisfactory aesthetic and functional recovery.
1 citations
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May 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” In laboratory studies on mice, Abstract UT-018, a stem cell chemoattractant formulation, was reported to significantly enhance wound healing and promote hair regeneration through mechanisms involving improved tissue formation, collagen organization, and follicular development.
September 2025 in “Frontiers in Medicine” This study found that angiopoietin-1 significantly reduces apoptosis and promotes proliferation in human follicle dermal papilla cells under DHT-induced stress, suggesting its potential as a therapeutic candidate for androgenetic alopecia.
August 2025 in “Journal of Cosmetic Dermatology” This review explores low-level light therapy's potential as a noninvasive treatment for various forms of alopecia, noting its promising results in hair regrowth and density but highlighting the need for standardized protocols and further research.
May 2025 in “Arquivos Catarinenses de Medicina” In this case report, an 8-year-old girl with burn-induced cicatricial alopecia showed improved graft survival after hair transplantation due to preparatory microfat grafting, which enhanced tissue conditions and possibly increased follicular unit survival rates to about 80%, higher than typically expected.
March 2025 in “International Journal of Trichology” In this case report, researchers described a treatment for post-aplasia cutis congenita alopecia using follicular unit transplantation, platelet-rich plasma, and fat grafting, which significantly improved hair follicles, skin quality, and sensitivity in the affected scalp area.
May 2026 in “Stem Cell Research & Therapy” This study found that exosomes derived from dental pulp mesenchymal stem cells (DPSC-Exos) significantly promoted hair regrowth and follicle density in a mouse model of androgenetic alopecia, showing similar efficacy to minoxidil by activating pathways that improve follicular vascularization and dermal papilla cell function.
August 2025 in “Revista Contemporânea” This study reviewed literature on the combined use of microneedling and essential oils for treating male androgenetic alopecia, finding that this approach potentially enhances scalp vascularization and hair growth, although controlled clinical trials are needed to confirm these effects and standardize treatment protocols.
211 citations
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February 2009 in “European journal of pharmaceutics and biopharmaceutics” This review summarizes recent advancements in follicular targeting for drug delivery via hair follicles and calls for pilot studies in humans to explore potential clinical applications.
69 citations
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September 2006 in “Human Reproduction” This study found that CD45RO+ cells, a subtype of T lymphocytes, were notably reduced in the ovarian follicles of women with PCOS, which may contribute to the condition's pathogenesis.
16 citations
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April 2016 in “PLoS ONE” In a porcine model, this study observed that using an External Tissue Expansion Device increased epidermis thickness, cell proliferation, and vessel density at fat graft recipient sites.
13 citations
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December 2019 in “Nutrients” In human follicular cells, this study found that an Annurca apple-based dietary supplement may stimulate the production of hair keratins, suggesting potential benefits for hair growth.
11 citations
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August 2017 in “American Journal of Dermatopathology” This study found that the Elastic Verhoeff–Van Gieson stain may help differentiate between follicular streamers and scars in cicatricial and noncicatricial alopecias by highlighting differences in the elastic fiber network on horizontal scalp biopsy sections.
May 2023 in “Brazilian Journal of Animal and Environmental Research” In this study, photobiomodulation therapy using EccoVet® equipment was applied to a canine patient with alopecia, leading to noticeable hair regrowth after just one session and complete improvement after five, highlighting its potential as a fast, non-invasive treatment for canine alopecia.
28 citations
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July 2011 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This case report describes a serious complication of follicular unit extraction, where donor-site necrosis led to cicatricial alopecia, but was successfully treated with two-stage surgery using tissue expanders.
14 citations
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December 2010 in “Journal of human genetics” This study identified a severe MBTPS2 gene mutation in a Japanese patient with IFAP syndrome, suggesting other factors may influence the varied clinical severity of the condition.
9 citations
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January 2021 in “RSC Advances” Non-thermal plasma helps hair grow by improving the area around hair follicles.
December 2025 in “Clinical Cosmetic and Investigational Dermatology” In this report, a unique female presentation of IFAP syndrome is described, featuring musculoskeletal contractures but no photophobia, highlighting the importance of early detection and multidisciplinary care to improve outcomes and prevent disability.