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Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Hibiscus rosa-sinensis leaf extract helps hair grow longer and faster.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Finasteride effectively treats baldness but may cause sexual side effects.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.

Liposomes could improve how skin care products work but are costly and not very stable.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Lowering testosterone speeds up wound healing in male mice.