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Skin aging reflects overall body aging and can indicate internal health conditions.

Alopecia in patients with epidermolysis bullosa varies in severity and is often caused by skin blistering or trauma.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Higher early lead exposure is linked to delayed puberty in girls.

Environmental factors can cause mutations in skin proteins, leading to skin disorders.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

Women's hair generally gets thinner and less dense starting in their mid-thirties, with hair loss becoming more common as they age due to both genetics and environment.

Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.

The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.

The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.

Niosomes can effectively deliver Superoxide Dismutase to hair follicles, potentially helping prevent hair loss.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

The study found that diseases can be grouped by symptoms and that the accuracy of predicting disease-related genes varies with the data source.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.