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The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

The new rodent model successfully mimics non-lean human PCOS symptoms.

An 8-year-old girl has a rare, irreversible hair loss condition caused by a genetic mutation.

Oral contraceptives provide various health benefits beyond birth control, including managing menstrual issues, skin conditions, pain, and reducing the risk of certain cancers.

Steven Kossard classified lymphocyte-related hair loss into four patterns, each linked to different types of baldness.

Milia may come from the outer part of the hair follicle.

Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.

Trichoscopy helps tell apart Frontal Fibrosing Alopecia and Lichen planopilaris by showing different hair and scalp features.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Researchers found a new mutation causing total hair loss from birth.

A mutation in the HR gene causes a rare form of irreversible hair loss in two Kashmiri families. Whole exome sequencing is effective for finding such mutations.

Overexpression of HDGF in melanocytes does not cause cancer.

Agaricus subrufescens improves ovarian function and biochemical health in rats with PCOS.

Proper nutrition can help manage PCOS symptoms and improve overall health.

A misdiagnosed case of HAIR-AN syndrome led to unnecessary surgeries and highlighted the importance of correct diagnosis and treatment.

The woman's rare combination of diseases suggests an unknown factor may predispose individuals to multiple endocrine diseases.

The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.

Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.

Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Folliculotropic mycosis fungoides has a worse prognosis than other types, with survival rates varying significantly based on subtype and organ involvement.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.