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Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Chemotherapy often causes hair loss, which usually grows back within 3 to 6 months, but there's no effective treatment to prevent it.

New hair loss treatments may include topical medications, injections, and improved transplant methods.

A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.

Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

EGF controls hair growth by regulating hair follicles' growth phases.

Both estrogens and androgens are important for health in both males and females.

17-β-Estradiol applied to the skin stops hair growth, while ICI 182 780 helps hair grow in mice.

Low-dose finasteride effectively reduces hirsutism without serious side-effects.

Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.

Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.

Caffeine may help hair growth in hereditary hair loss.

PRP helps hair growth in common hair loss disorder.

Using your own blood (PRP) can effectively increase hair count and strength in men with hair loss.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.

Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.