49 citations
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January 2010 in “Plant and Cell Physiology” This study found that a phosphorus starvation-insensitive mutant of Arabidopsis thaliana shows altered root growth and auxin responses under low phosphate conditions compared to wild-type plants, suggesting a role for LPR1 in regulating these traits.
This study demonstrated that Reverse Protein Engineering can decrease the size of Firefly Luciferase from 550 to less than 80 amino acids, but further research is needed to ensure these smaller peptides retain bioluminescent activity.
3 citations
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September 2024 in “BMC Oral Health” This study found that low-level laser therapy effectively reduced relapse rates, while functional appliances did not; combining them offered no additional benefits.
July 2022 in “Research Square (Research Square)” This study found that Egyptian women with frontal fibrosing alopecia had lower serum PPARγ levels and a higher occurrence of PPARG gene polymorphism compared to healthy controls, suggesting a potential role for PPARγ in the condition's development.
1 citations
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December 2018 in “Journal of genetic medicine” In this case report, a 20-year-old male with tricho-rhino-phalangeal syndrome was found to have a de novo frameshift mutation in the TRPS1 gene, highlighting the challenges in diagnosing this rare disorder.
July 2015 in “Journal of the Dermatology Nurses’ Association” This review covers the clinical presentation and challenges in treating frontal fibrosing alopecia in postmenopausal women and concludes that more research is needed to understand its etiology and develop effective treatments.
18 citations
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July 2016 in “Journal of The American Academy of Dermatology” This study reported that both primary and secondary cutaneous follicle center lymphomas can present with atypical scalp or forehead lesions, leading to potential misdiagnosis as other skin conditions.
9 citations
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January 2023 in “Journal of Clinical Medicine” This study presents a validated questionnaire, the FFA-QLI, which effectively assesses and differentiates the quality of life impact among patients with frontal fibrosing alopecia, showing greater sensitivity in identifying severe cases than the DLQI.
125 citations
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February 2007 in “The EMBO Journal” Fgfr2b helps maintain healthy skin and prevent cancer.
2 citations
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March 2021 in “Dermatologic Therapy” This study found that low-level laser therapy significantly increased hair counts in women with female pattern hair loss but not in those with telogen effluvium, without serious adverse events.
July 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study developed a potent Wnt surrogate with high specificity for the Fzd7 receptor in mice, promoting full hair follicle regeneration and robust hair growth, suggesting potential applications in tissue development and targeted regeneration.
3 citations
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January 2018 in “International Journal of Trichology” The authors concluded that their new grading system can effectively classify early female pattern hair loss and evaluate treatment progress.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers conducted an exploratory re-analysis of miRNA dysregulation and aging-related target enrichment using publicly available data on female pattern hair loss, comparing 3 FPHL scalp samples to 5 healthy female controls, and emphasized that the findings are preliminary and require further validation.
1 citations
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October 2024 in “Canine Medicine and Genetics” This study suggests a potential genetic component in CFA among Ridgeback dogs, but MLPH genotyping did not identify the MLPH gene as a contributing factor.
12 citations
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June 2020 in “The anatomical record” This study found that miR-203a-3p downregulates Smad1, promoting the differentiation of loureirin A-induced hair follicle stem cells, suggesting it could be a potential therapeutic target for skin wound healing.
May 2024 in “Journal of Cosmetic and Laser Therapy” This study found that three sessions of injectable platelet-rich fibrin (i-PRF+) significantly improved hair follicle density, hair volume, and thickness, as well as patient satisfaction in women with female pattern hair loss, with only minor self-limited adverse effects reported.
8 citations
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August 2017 in “Skin appendage disorders” Red dots on the upper chest may be an early sign of certain types of hair loss.
37 citations
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January 2023 in “Ophthalmology and Therapy” In this study, more than 25% of children experienced axial length shortening greater than 0.05 mm/year following repeated low-level red-light therapy.
21 citations
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November 2017 in “Archives of Dermatological Research” This study found that women with female pattern hair loss had increased 5α-reductase isozymes and decreased aromatase mRNA levels, potentially affecting their response to treatment.
September 2023 in “World Rabbit Science” In this study using Angora rabbits, researchers found that the FRZB gene inhibits hair follicle development by modulating the Wnt/β-catenin signaling pathway, affecting the expression of various genes related to this pathway and altering cell proliferation and apoptosis.
January 2025 in “Bioengineering” This study evaluated the long-term effects of combining autologous platelet-rich stroma injection with transanal advancement flap repair for cryptoglandular transsphincteric fistulas and found that it resulted in primary clinical closure and radiological healing in a high percentage of patients, with low recurrence rates.
36 citations
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March 2014 in “Annals of the Rheumatic Diseases” This study found that activating liver X receptors with an agonist reduced skin fibrosis in experimental models, particularly in inflammation-driven conditions, by inhibiting macrophage infiltration and interleukin-6 release.
December 2025 in “ILDS-DEV”
October 2023 in “Journal of Advanced Sciences” This review highlights PRF's potential as a regenerative medicine tool, detailing its diverse applications in dentistry, orthopedics, and dermatology, but presents no new clinical results.
April 2019 in “Journal of Investigative Dermatology” This study identifies a mechanism where dsRNA activates TLR3 to induce RA production, promoting hair follicle regeneration in mice and suggesting a potential role in human tissue regeneration.
2 citations
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December 2020 in “Frontiers in genetics” In this study, the researchers identified the SPEF2 and PRLR genes as potential candidates associated with feather rate phenotypes in Shouguang chickens through combined genome-wide association and differential expression analyses.
155 citations
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September 2008 in “British journal of dermatology/British journal of dermatology, Supplement” This study observed that frontal fibrosing alopecia predominantly affects postmenopausal women, can be associated with lichen planus, and may lead to progressive hairline recession, though this progression is not consistent in all cases.
1 citations
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January 2023 in “Cutis” This report discusses two cases where patients continued EGFR inhibitor therapy while receiving topical treatments for SDRIFE, highlighting the importance of dermatologists in managing such cutaneous adverse events without stopping cancer treatment.
10 citations
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June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified FP-1 as a highly specific extracellular matrix protein in follicular papilla cells, which may play a role in hair growth regulation during specific hair cycle phases.
May 2024 in “Journal of the Egyptian Women's Dermatologic Society /Journal of the Egyptian Women's Dermatologic Society” In this split-scalp study, researchers observed that combining fractional CO2 laser and PRP treatment was significantly more effective in improving hair parameters in women with female pattern hair loss than using each intervention alone or placebo.