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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Ketoconazole shampoo improves hair growth and reduces oil similarly to minoxidil in male pattern hair loss.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.

Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.

A male with aromatase deficiency improved bone health with estradiol treatment.

Most skin changes during pregnancy go away after giving birth.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.

Systemic diseases can cause hair loss, which is often reversible with treatment.

The review concludes that accurate diagnosis of different types of hair loss requires proper biopsy techniques and understanding the hair growth cycle and underlying causes.

Higher fluoride levels may delay puberty in boys.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.