28 citations
,
August 2013 in “Hypertension” The authors concluded that diazoxide reduces undesirable side effects compared to minoxidil while increasing elastic fiber content and decreasing cell number in the aorta, suggesting potential suitability for treating vascular conditions with low arterial elastin and hypertension.
25 citations
,
April 2008 in “Archives of Dermatological Research” This study found that transplanted microencapsulated dermal papilla cells in rat footpads can regenerate hair follicles and sebaceous gland structures, suggesting a potential substitute for fresh dermal papillae cells.
23 citations
,
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” In this mouse study, NF-κB was shown to play a role in hair follicle cycling and morphogenesis, with specific activity patterns differing by hair type and involving noncanonical signaling for zigzag hair bending.
21 citations
,
March 2015 in “Journal of The American Academy of Dermatology” In this study, five out of six patients treated with vemurafenib for metastatic melanoma experienced hair loss, which improved after topical steroid treatment.
18 citations
,
November 2010 in “Journal of morphology” This research examined the ultrastructure of deer hair fibers and found significant variations in diameter, cuticle thickness, and intermediate filament arrangements among different fiber types.
17 citations
,
December 2002 in “Biochemical and biophysical research communications” This study reports on the biochemical characteristics of S100A3 protein in human hair cuticle, notably finding its N-terminal methionine is acetylated and has a slightly lower isoelectric point compared to the recombinant version.
15 citations
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July 2004 in “Journal of morphology” This study analyzes the fine structure and protein distribution in monotreme hairs, finding similarities with other mammals and detailing unique immunocytochemical features in their inner root sheaths.
15 citations
,
February 1999 in “The anatomical record” This study found that defective cross-linking in hair cuticles is observable in a minority of mouse hair mutants, suggesting different proteins are involved in cross-linking across cell types.
14 citations
,
June 2001 in “Endocrinology” This study found that disrupting the PRL gene in mice alters the timing of hair cycling events, causing earlier molts and changes in hair characteristics, particularly affecting female mice more significantly.
13 citations
,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” This review covers various aspects of hair biology, pigmentation, and development, focusing on genetic and biochemical modulation of hair follicle components but reports no new findings.
12 citations
,
January 2007 in “Current problems in dermatology” This review discusses the impact of various exogenous agents on hair, such as cosmetics and radiation, but reports no new experimental results.
11 citations
,
August 2017 in “American Journal of Dermatopathology” This study found that the Elastic Verhoeff–Van Gieson stain may help differentiate between follicular streamers and scars in cicatricial and noncicatricial alopecias by highlighting differences in the elastic fiber network on horizontal scalp biopsy sections.
11 citations
,
November 2009 in “Brazilian Journal of Medical and Biological Research” This study found that young C57BL/6 and BALB/c mice exhibit distinct regenerative patterns during ear wound healing, with greater wound closure but less regeneration in middle-aged C57BL/6 mice.
9 citations
,
July 2020 in “Journal of Animal Physiology and Animal Nutrition” This study found that maternal melatonin supplementation improved fur quality in Rex rabbit offspring by increasing hair follicle density and altering melatonin receptor gene expression in several organs.
5 citations
,
January 2018 in “International Journal of Trichology” This study found no significant difference in the tensile properties of hair from different scalp positions, suggesting that microscopic structural heterogeneities may play a role.
4 citations
,
April 2020 in “Facial Plastic Surgery Clinics of North America” This article reviews the comprehensive approach needed for hair restoration in women, including preoperative evaluations, distinguishing scarring alopecias, and managing postoperative hair shock loss, but reports no new clinical findings.
4 citations
,
January 2015 in “Sen'i Gakkaishi” This study proposed a network model for the cross-linked structure of keratin-associated proteins in hair and wool fibers, suggesting notable differences between the two, potentially affecting hair fiber elasticity.
4 citations
,
May 2012 in “Tissue Engineering and Regenerative Medicine” This study demonstrated the potential of epithelial cell scaffolds fabricated with various materials for effective hair regeneration, highlighting their promising application in tissue engineering for alopecia treatment.
4 citations
,
January 2007 in “Sen'i Gakkaishi” This study found that permanent wave treatment accelerates hair degradation after protease exposure, showing significant morphological differences compared to untreated hair and linked to damage from Alpha-helical region denaturation.
3 citations
,
August 2019 in “Journal of Animal Physiology and Animal Nutrition” This study found that the combined use of sugarcane fibre and keratinolytic enzymes reduced hairball excretion in cats.
2 citations
,
April 2017 in “Actas Dermo-Sifiliográficas” This review discusses the etiology, pathogenesis, clinical presentation, and treatment of frontal fibrosing alopecia, noting the lack of clinical trial data and limited observational treatment results.
2 citations
,
November 2014 This chapter reviews common cosmetic dermatology techniques but presents no new findings; it discusses treatments like emollients and laser therapy for conditions like photoaged skin and acne scarring.
This chapter provides an overview of the complex chemical and physical structure of the hair surface, detailing how factors like ethnicity, environmental stress, and cosmetic treatments can alter its properties and influence the adhesion of hair care products.
1 citations
,
December 2015 in “The Egyptian Journal of Histology” This study found that experimentally induced hypothyroidism in rats is associated with impaired skin structure, but topical application of triiodothyronine (T3) improved these changes to resemble normal skin.
1 citations
,
December 2014 in “Scanning” This study used multiphoton microscopy to successfully visualize rabbit skin microstructure, highlighting its noninvasive potential for future skin research related to diseases and wound healing.
November 2025 in “Nature Communications” This study used a 3D live imaging system to map cell dynamics in human hair follicles, revealing patterns of cell movement and division that help explain hair fiber extrusion during hair growth.
October 2025 in “International Journal For Multidisciplinary Research” This review describes evidence suggesting regular apple consumption may improve cardiovascular health and reduce risks for chronic diseases through antioxidant, anti-inflammatory, and other beneficial effects, particularly when consumed as whole fruits rather than processed forms.
September 2025 in “Sahel Journal of Life Sciences FUDMA” This study reported that albino Wistar rats exposed to chemical hair straighteners showed significant hair fiber damage and scalp skin deterioration, which worsened with repeated and prolonged application, highlighting the cytotoxic potential of these products and potential systemic risks.
This study reports that in Rex rabbits, age affects fur quality and hair follicle traits, with the Wnt signaling pathway playing a role in their periodic hair follicle development.
January 2024 in “Journal of Material Cycles and Waste Management” Adding human hair to cement can make it tougher and better insulated but also more porous.