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High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Targeted cancer therapies often cause serious skin problems that need careful management.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Some medicinal plants can help heal wounds and may lead to new treatments.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

CDP is crucial for lung and hair follicle cell development.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Forehead modification greatly increases the perception of femininity and is a safe procedure.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Metformin improves hair growth and menstrual frequency in women with PCOS and hirsutism.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.