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PCOS is a hormonal disorder causing infertility and menstrual problems, often linked to obesity and can lead to acne, treated with hormonal and insulin-sensitizing medications.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.

Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Treatment during development affects hormone balance and sexual behavior in male rats.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

Overexpressing SIMK in alfalfa boosts root hair growth, nodule clustering, and shoot biomass.

Androgens increase EPO production, finasteride doesn't significantly impact it.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

Oxidative stress may contribute to hair loss in alopecia areata and antioxidants could potentially help as a treatment.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

Chemotherapy can cause skin side effects that affect patients' lives, but they can be managed to avoid interrupting cancer treatment.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Fungi-produced compounds can change plant root growth.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.