37 citations
,
June 2011 in “Journal of Cellular Biochemistry” In this study, transgenic male mice over-expressing the androgen receptor in mesenchymal stem cells showed reduced fat mass and improved glucose clearance, suggesting enhanced androgen sensitivity may alter body composition.
25 citations
,
July 2020 in “Journal of cosmetic dermatology” In this study, the authors reported that while deoxycholic acid effectively reduces submental fat, it can cause adverse effects such as edema, numbness, and skin necrosis, making knowledge of possible complications essential for clinicians.
10 citations
,
September 2013 in “Nutrition” In this animal study, the ketogenic diet was associated with more severe biotin deficiency in biotin-deficient mice, suggesting that biotin supplementation is important when following this diet.
5 citations
,
April 2021 in “Journal of Mind and Medical Sciences” This review examines the interconnected roles of bone, adipose tissue, and the central nervous system in regulating energy balance, providing no new experimental results.
5 citations
,
February 2011 in “Aesthetic Plastic Surgery” This study describes a novel intraoral approach for lower eyelid fat transposition and midface lift, reporting improved outcomes and visualization without complications such as lower eyelid malposition or asymmetry in six patients.
2 citations
,
October 2021 in “Bioinformation” This study found that the FTO gene variants rs17817449 and rs1421085 were significantly associated with PCOS susceptibility, and rs8050136 was linked with hair loss and high BMI in women with PCOS in western Saudi Arabia.
September 2025 in “Skin Research and Technology” July 2025 in “Journal of Investigative Dermatology” Nelfb is essential for dermal fat development and survival.
April 2021 in “Journal of Investigative Dermatology” Blocking DPP4 can help prevent fat loss and skin fibrosis.
September 2018 in “Plastic and Reconstructive Surgery – Global Open” This study found that real-time ultrasound-assisted gluteal fat grafting effectively allowed surgeons to verify subcutaneous fat injection, potentially reducing risks of major complications, though it involved increased costs, surgical time, and a learning curve.
128 citations
,
December 2006 in “Journal of Biological Chemistry” This study found that overexpression of the enzyme spermidine/spermine N1-acetyltransferase in mice was associated with increased fat oxidation and a leaner phenotype, while knock-out mice exhibited increased fat accumulation.
31 citations
,
May 2017 in “JAAD Case Reports” This article reviews the use of deoxycholic acid as a nonsurgical treatment for unwanted fat in the cosmetic field but reports no new clinical results.
10 citations
,
July 2023 in “The Neuroscience Journal of Shefaye Khatam” In this review, the authors summarized the neuroprotective role of water- and fat-soluble vitamins in neurodegenerative diseases, highlighting their potential preventive and therapeutic effects through antioxidant and anti-inflammatory properties while acknowledging some studies question their preventive influence.
1 citations
,
August 2025 in “Genes” This study identified genetic variations that could serve as candidate markers for improving body conformation traits in Kazakh fat-tailed coarse-wool sheep through marker-assisted selection.
October 2025 in “Journal of the Endocrine Society” The researchers reported that individuals with non-alcoholic fatty liver disease and nutritional deficiency often exhibit iron and estrogen deficiencies, which may contribute to liver cell stress and fibrosis.
January 2024 in “Journal of Hard Tissue Biology” In this study, researchers found that a high-fat diet in mice induced downregulation of certain Krtap genes in the tongue, which may be linked to structural issues or oral cancer risk, highlighting a potential connection between oral health and systemic diseases like metabolic syndrome.
December 2022 in “Zenodo (CERN European Organization for Nuclear Research)” Puradrop Extra Strength Gummies claim to support weight loss and boost energy using natural ingredients.
January 2019 in “Dermatologic Surgery” This overview discusses the Dermatologic Surgery journal and reports no new clinical results; it compiles comprehensive peer-reviewed content on cosmetic and reconstructive skin surgery and skin cancer.
16 citations
,
August 2014 in “PubMed” October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This article describes the promoted benefits of Ignite Amazonian Sunrise Drops for weight management and metabolism, but it reports no new scientific results.
March 2026 in “Journal of obstetrics and gynaecology research” In this study, Ark-e-Kasni was found to alleviate PCOS symptoms in rats by restoring hormonal levels, improving insulin sensitivity, and reducing inflammation and cystic follicles, suggesting its therapeutic potential via diverse molecular mechanisms.
May 2025 in “Journal of Experimental Pharmacology” This study found that Allium ascalonicum L. extract may improve insulin resistance by increasing insulin tolerance test values and lowering blood glucose levels, though more research is needed to understand its effects on metabolic disorders.
10 citations
,
November 2019 in “Journal of Traditional and Complementary Medicine” This study found that oral treatment with Chamaecyparis obtusa var. formosana leaf extracts improved glucose metabolism and reduced insulin resistance in hyperglycemic rats, suggesting potential as a diabetes health supplement.
499 citations
,
September 2011 in “Cell” This study found that intradermal adipocyte lineage cells in mice are necessary and sufficient to activate follicular stem cells, highlighting their role in regulating skin stem cell activity.
316 citations
,
June 2017 in “Stem Cell Research & Therapy” This review covers the potential of SVF and ADSC therapies in regenerative medicine and highlights the challenges of regulation and efficacy, without reporting new clinical results.
301 citations
,
February 2019 in “Nature Communications” In this study, researchers found that wound healing in mouse skin recruits diverse fibroblasts, including myeloid-derived cells, which contribute to regenerating adipocytes.
299 citations
,
January 2018 in “Journal of Clinical Investigation” This review explores fibroblast heterogeneity in the mammalian dermis and suggests potential therapeutic applications by targeting fibroblast subtypes, but reports no new experimental results.
238 citations
,
March 2013 in “Development” This study found that adipocytes play a crucial role in skin wound healing by facilitating fibroblast recruitment and dermal reconstruction during the healing process.
218 citations
,
May 2014 in “Experimental Dermatology” This review explores the evolution and development of skin-associated adipose tissue and proposes new nomenclature for the cells and adipose tissue underlying the reticular dermis, without reporting clinical results.