Linking the Brain and Bone Through Fat

This study found that androgen signaling has complex effects on bone formation in male AR3.6-transgenic mice, with varying impacts based on the embryonic lineage of cells.

This review discusses the use of spinal fMRI to investigate the brainstem and spinal cord and highlights its potential for understanding functional integration, but it reports no new experimental results.

This study utilized a mouse model of traumatic brain injury to reveal that acute neurotrauma triggers widespread lipid metabolism reprogramming and storage lipid accumulation in microglial and monocyte populations, leading to lysosomal dysfunction, inhibited autophagy, and exacerbated inflammation through a pathological feedback loop.

Turning scar-forming cells into fat cells can reduce scarring.