Protective Effect of Ark-E-Kasni, a Unani Formulation, in Letrozole and High-Fat Diet-Induced Polycystic Ovarian Syndrome in Rats

    March 2026 in “ Journal of obstetrics and gynaecology research ”
    Kamini R Shirasath, Ritu Karwasra, N. Zaheer Ahmed … Yogeeta O. Agrawal
    Studysummary In this study, Ark-e-Kasni was found to alleviate PCOS symptoms in rats by restoring hormonal levels, improving insulin sensitivity, and reducing inflammation and cystic follicles, suggesting its therapeutic potential via diverse molecular mechanisms.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on obgyn.onlinelibrary.wiley.com →
    Discuss this study in the Community →

    Research cited in this study 6

    1. Physiopathology of Polycystic Ovary Syndrome in Endocrinology, Metabolism, and Inflammation Journal of Ovarian Research · 2025
    2. Alternative Treatment of Polycystic Ovary Syndrome: Pre-Clinical and Clinical Basis for Using Plant-Based Drugs Frontiers in Endocrinology · 2024
    3. Polycystic Ovary Syndrome: Etiology, Current Management, and Future Therapeutics Journal of Clinical Medicine · 2023
    4. Role of Oxidative Stress in Obese and Nonobese PCOS Patients International Journal of Clinical Practice · 2022
    5. Mechanistic and Therapeutic Insight into the Effects of Cinnamon in Polycystic Ovary Syndrome: A Systematic Review Journal of Ovarian Research · 2021
    6. Pregnancy and Neonatal Outcome with Maternal Exposure to Finasteride: Case Series Journal of Dermatology and Dermatologic Surgery · 2021