30 citations
,
August 2021 in “Oncogene” This study reports that miR-22 promotes cancer progression and metastasis by maintaining Wnt/β-catenin signaling and cancer stem cell function.
20 citations
,
December 2019 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” In this study, ustekinumab did not promote hair regrowth in human patients with alopecia areata or prevent disease development in an AA mouse model, suggesting limited efficacy for this treatment.
14 citations
,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” This study reported that the compound (1R, 2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile effectively stimulated hair growth in mice and reduced sebum production in hamsters.
2 citations
,
January 2025 in “Frontiers in Pharmacology” In a rat model of benign prostatic hyperplasia, this study found that purple corn extract may improve symptoms by inhibiting prostate enlargement, reducing androgen receptor signaling, and exerting anti-inflammatory effects.
June 2025 in “Animal Bioscience” This study found that miRNA-24 downregulates the KLF6 gene, influencing coat color by affecting melanogenesis pathways in Cashmere goats, and that miRNA-24 inhibition increased melanin content in mice.
In this case report, a 25-year-old female with Mixed Connective Tissue Disease presented unusual symptoms in a specific geographical region, prompting clinicians to approach diagnosis and management with caution due to potential severe complications such as pulmonary hypertension and renal crisis.
89 citations
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March 1996 in “Proceedings of the National Academy of Sciences” This study found that homozygous mutant mice with a hypomorphic CD18 mutation developed a chronic inflammatory skin disease resembling human psoriasis, potentially implicating additional genetic factors in disease susceptibility.
51 citations
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November 2020 in “Journal of the European Academy of Dermatology and Venereology” This article discusses SARS-CoV-2-induced telogen effluvium in a multicentric study and reports no new clinical results.
13 citations
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January 2018 in “Annals of Dermatology” Alopecia areata and androgenetic alopecia affect quality of life similarly.
12 citations
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June 2020 in “Frontiers in Cell and Developmental Biology” This study found that the PP2A-B55α regulatory subunit is crucial for ectodermal development in mice, with knockout embryos displaying severe neural and epidermal defects and failing to survive to birth.
6 citations
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January 2013 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” In this study, TASP0382088 showed potent selective inhibition of the ALK5 receptor, significantly reducing Smad2 phosphorylation in mouse skin following topical application.
6 citations
,
January 2005 in “Biology of Blood and Marrow Transplantation” This article reviews various models of graft-versus-host disease, highlighting the complexity of its mechanisms and the challenges in interpreting histopathologic data; it reports no new results.
This study found that ocu-miR-205 affects signaling pathways, promoting the apoptosis of dermal papilla cells and influencing hair follicle density in Rex rabbits.
2 citations
,
January 2024 in “IEEE Access” This study introduces AlopeciaDet, a novel feature fusion technique, using camera images to detect Alopecia Areata with 99.45% accuracy, outperforming existing methods by leveraging CRSHOG and ResNet-50 features.
This study found that ocu-miR-205 promotes apoptosis in dermal papilla cells, alters hair follicle signaling pathways, and affects hair density in Rex rabbits.
This study found that a deep learning framework using the ResNet50 model achieved 95% overall accuracy in classifying 10 categories of hair diseases, demonstrating reliable performance but also identifying potential improvements due to misclassifications between similar conditions.
January 2024 in “Wiadomości Lekarskie” This study reports how the Polish-American Medical Society (ZLP Chicago) played a proactive role during the COVID-19 pandemic in the Chicago area, leading efforts in public education, support for administrative measures, and dissemination of health guidelines to the Polish community.
August 2019 in “Placenta” This article reviews the use of spironolactone in dermatology for conditions like female acne, suggesting it may reduce antibiotic and isotretinoin use, and stresses its long-term safety.
December 2024 in “European Journal of Medicinal Plants” This study developed a polyherbal powder shampoo utilizing natural ingredients, with formulation F6 demonstrating optimal cleaning action and foaming index, along with satisfactory physicochemical properties, making it the preferred formula among the tested variations.
34 citations
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April 2007 in “Neuroscience” In this study, finasteride altered acute ethanol withdrawal severity differently in male and female mice, highlighting sex differences in sensitivity to changes in neurosteroid levels.
January 2017 in “Nasza Dermatologia Online” This study found that both new and old formulas of DCP for treating alopecia areata resulted in similar hair regrowth, but tolerance was significantly better with DCP in isopropanol.
September 2020 in “arXiv (Cornell University)” This study demonstrated that a computational screening process can identify existing drugs and natural compounds with potential anti-COVID-19 activity, highlighting some candidates for further experimental validation.
2 citations
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February 2014 in “Animal Biotechnology” This study reported that the PTGER2 gene is strongly expressed in cashmere goat skin and its expression tends to decrease from the anagen to telogen stages of the hair follicle cycle.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” In a keratinocyte-specific knockout mouse model, this study found that deleting GRK2 disrupted hair follicle homeostasis, causing cyst-like structures, abnormal growth patterns, and eventual hair loss, suggesting potential links to immune-mediated alopecias.
May 2011 in “Value in Health” This study found that the oral Janus kinase inhibitor CP-690,550 has a direct effect on reducing pruritus in patients with psoriasis, independent of clinician-assessed improvements in psoriasis severity.
53 citations
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February 2017 in “Journal of The American Academy of Dermatology” In this study of 20 patients with erosive pustular dermatosis of the scalp, using trichoscopy improved diagnosis, and treatments with high-potency steroids or topical tacrolimus effectively reduced inflammatory signs, suggesting these as first-line treatments.
March 2026 in “Voprosy dermatologii i venerologii/Dermatologiâ ža̋ne veneralogiâ ma̋selelerì” This study conducted among sex workers in Kostanay reported a low HIV prevalence of 0.8% but a high syphilis rate of 15.6%, highlighting significant social risks and emphasizing the need to expand pre-exposure prophylaxis and prevention programs.
October 2023 in “Journal of Medicine, University of Santo Tomas (JMUST Online)” This study reported that among Filipino elderly patients, xerosis/xerotic eczema was the most common dermatological condition leading to consultation, with inflammatory dermatoses being the predominant category of skin diseases observed from 2014 to 2018 at a tertiary hospital's dermatology service.
3 citations
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May 2021 in “British Journal of Dermatology” This study reports that COVID-19 significantly decreased skin cancer diagnoses and referrals, with reductions of up to 60% observed in the Netherlands and similar trends in the UK and Australia.
8 citations
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November 2018 in “Australasian Journal of Dermatology” This study adds evidence suggesting a genetic component to frontal fibrosing alopecia, with daughters experiencing an earlier onset than their mothers, although the clinical pattern remains similar to non-familial cases.