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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.

Siblings with signs of virilization should be tested for non-classical congenital adrenal hyperplasia, which does not affect adult height but may impact fertility and well-being if untreated.

Eating dairy and high glycemic foods may increase the risk of acne.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Only skin melanocytes, not other types, can color hair in mice.

Changes in the HR gene have influenced hair growth and may lead to hair loss conditions in humans.

Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Iron deficiency might contribute to hair loss in women.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Fat-derived stem cells and their secretions show promise for treating skin aging and hair loss.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Different types of sun exposure can damage skin cells and affect healing, with chronic exposure being more harmful, and certain immune cells help in the repair process.

Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.

Epidermal stem cells don't use gap junctions to communicate.

The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.

People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Cyclosporin A promotes hair cell growth and affects protein kinase C levels.

Mesenchymal stem cells could help treat aging-related diseases better than current methods.

Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.

Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.

Sweat glands and hair follicles are determined by opposing signals, with BMPs promoting sweat glands and blocking BMPs leading to hair follicles.

The study found a link between the severity of Lichen Planopilaris seen by doctors and the details seen under a microscope, and created a new way to measure this severity.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

The document concludes that proper diagnosis and treatment of follicular disorders are crucial, with specific treatments for conditions like acne, drug-induced eruptions, and rosacea.

Human skin can make serotonin and melatonin.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.