14 citations
,
January 1998 in “Dermatology” This study found evidence that polythelia pilosa, previously excluded from classification, should be reintroduced as it marks true aberrant mammary structures in men and hirsute women.
13 citations
,
October 2021 in “Actas Dermo-Sifiliográficas” This review examines existing evidence on scalp cooling systems to prevent or reduce chemotherapy-induced hair loss in cancer patients, noting promising results and their increasing adoption in clinical practice.
13 citations
,
April 2009 in “PLOS ONE” This study found no evidence that androgen receptor copy number variation is associated with androgenetic alopecia, suggesting it is unlikely to be a contributing factor.
13 citations
,
August 1991 in “The Journal of the American Osteopathic Association” This research found evidence of inflammatory involvement in androgenetic alopecia, with higher deposition of certain immune components in the scalp of affected patients compared to those without baldness.
12 citations
,
March 2023 in “Frontiers in immunology” This study found evidence that atopic dermatitis may increase the risk of developing rheumatoid arthritis, type 1 diabetes, and alopecia areata, but not other autoimmune diseases.
12 citations
,
July 2022 in “Journal of Cosmetic Dermatology” This review identifies existing evidence on the connection between COVID-19 and hair loss, suggesting that hair loss associated with COVID-19 may primarily involve telogen effluvium and be reversible.
12 citations
,
July 2019 in “Acta Neurologica Belgica” This review evaluated the evidence on skin disorders linked to levodopa treatment for Parkinson's disease, suggesting a possible association with melanoma, though evidence remains inconclusive and further studies are needed.
12 citations
,
May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” This review found insufficient evidence to determine methotrexate's effectiveness for maintaining regrowth in extensive alopecia areata, and suggests its potential role in inducing regrowth when combined with corticosteroids.
11 citations
,
March 2019 in “Journal of The American Academy of Dermatology” This review identifies evidence of sexual adverse effects, particularly linked to finasteride, in men using systemic dermatologic medications but reports no new clinical findings.
11 citations
,
April 2022 in “Journal of Dermatological Treatment” This review found evidence supporting zinc use in treating infectious and inflammatory skin conditions, as well as hair loss, with supplementation recommended for zinc-deficient patients.
11 citations
,
April 2020 in “Journal of The American Academy of Dermatology” This commentary reviews the evidence for microinflammation's role in pattern hair loss and suggests that further studies with age- and sex-matched controls are needed to substantiate the findings.
11 citations
,
January 2019 in “Dermatologic Therapy” This review found insufficient evidence to support the use of platelet rich plasma procedures for treating androgenetic alopecia.
10 citations
,
July 2021 in “International Journal of Rheumatic Diseases” This review summarizes evidence indicating that body image issues in patients with systemic lupus erythematosus should be addressed with the same importance as physical symptoms like pain and disability.
9 citations
,
May 2024 in “Journal of Clinical & Translational Endocrinology” This review examines existing evidence on the efficacy and safety of gender affirming hormone therapy in relation to Gender Affirmation Surgery, but reports no new clinical results.
9 citations
,
July 2018 in “European journal of dermatology/EJD. European journal of dermatology” This study provides evidence that long-term deregulation of the circadian rhythm in humans affects the regenerative properties of skin and hair precursor cells by altering clock pathway protein expression.
8 citations
,
November 2018 in “Australasian Journal of Dermatology” This study adds evidence suggesting a genetic component to frontal fibrosing alopecia, with daughters experiencing an earlier onset than their mothers, although the clinical pattern remains similar to non-familial cases.
8 citations
,
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study provides definitive evidence that a homozygous mutation in the DSC3 gene causes skin fragility and hypotrichosis in humans.
8 citations
,
January 2012 This review compiles scientific evidence on the effects of green tea polyphenols on cosmetic issues like aging and acne, but reports no new clinical results.
7 citations
,
March 2019 in “Cancer Epidemiology, Biomarkers & Prevention” This study found no evidence that finasteride use is associated with an increased risk of male breast cancer.
7 citations
,
December 2016 in “British Journal of Dermatology” This report presents evidence that alopecia areata incognita may be a possible mechanism of hair loss in patients with Cronkhite–Canada syndrome.
7 citations
,
March 2012 in “Journal of Investigative Dermatology” This study presents evidence that specific thymus-derived peptides affect human hair follicle growth, identifying thymulin as a potential hair growth stimulator despite interindividual response variations.
7 citations
,
October 2011 in “BMC Cancer” This study found no evidence that HDGF expression transforms melanocytes into tumors in a mouse model, although it may play a role in cell differentiation and tumor progression.
7 citations
,
April 2008 in “Annals of pharmacotherapy/The annals of pharmacotherapy” This review discusses the use of acarbose for managing polycystic ovary syndrome and notes positive but limited evidence from small trials, indicating a need for more rigorous studies.
6 citations
,
September 2024 in “Current Oncology” This review summarizes evidence and adverse event management recommendations for Sacituzumab Govitecan in metastatic triple-negative breast cancer and hormone receptor-positive breast cancer, emphasizing favorable survival data from clinical trials.
6 citations
,
February 2022 in “Actas Dermo-Sifiliográficas” This review examines evidence on the effectiveness of cold caps or scalp cooling systems in reducing chemotherapy-induced hair loss, but it reports no new clinical results.
5 citations
,
April 2025 in “Journal of Cosmetic Dermatology” This study evaluated eight JAK inhibitor regimens for alopecia areata and provided high-quality evidence on their comparative effectiveness, which can aid clinicians in decision-making and inform medical practice guidelines.
5 citations
,
January 2024 in “Journal of the American Academy of Dermatology” This study provided 18 evidence-based recommendations for managing acne vulgaris, strongly endorsing treatments like benzoyl peroxide, topical retinoids, and oral isotretinoin for severe cases, and issued conditional recommendations for therapies like salicylic acid and spironolactone, while offering good practice statements on combining treatment methods.
5 citations
,
July 2022 in “Journal of Clinical Medicine” This study found histopathological evidence of hypertrophy in nerve endings that may explain the cutaneous neurosensory symptoms in some long COVID-19 patients.
5 citations
,
May 2021 in “International Journal of Cosmetic Science” This review discusses the evidence for a cause-and-effect relationship between scalp condition and hair condition, and reports no new clinical results from trials.
5 citations
,
January 2021 in “Skin appendage disorders” This review summarizes evidence suggesting that smoking is associated with alopecia and premature hair graying, with smokers showing higher prevalence than nonsmokers.