research Adrenal Cortex Tumors and Hyperplasias
Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.
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research Pharmacokinetic-Pharmacodynamic Modeling Approach for Dose Prediction of the Optimal Long-Acting Injectable Formulation of Finasteride
Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.
research Parathyroid Hormone-Related Protein and the PTH Receptor Regulate Angiogenesis of the Skin
PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.
research Ascorbigen Induces Dermal Papilla Cell Proliferation In Vitro, But Fails To Modulate Chemotherapy-Induced Alopecia In Vivo
Ascorbigen increases hair cell growth in a lab setting but does not prevent hair loss from chemotherapy in mice.
research MiR-218-5p Regulates Skin and Hair Follicle Development Through Wnt/β-Catenin Signaling Pathway by Targeting SFRP2
miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.
research Artepillin C and Other Herbal PAK1-Blockers: Effects on Hair Cell Proliferation and Related PAK1-Dependent Biological Function in Cell Culture
Certain herbal compounds, especially from bitter melon, can inhibit cancer growth and promote hair growth by blocking PAK1.
research Spironolactone May Be a Cause of Hormonally Associated Vestibulodynia and Female Sexual Arousal Disorder
Spironolactone might cause painful intercourse and decreased sexual arousal in women.
research Deoxycorticosterone’s Anticonvulsant Effects in Infant Rats Are Blocked by Finasteride, but Not by Indomethacin
Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
research Dupilumab: A Review of Present Indications and Off-Label Uses
Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
research How Does Altered Metabolism Lead to Seizure Control? Partially Filling the Knowledge Gap
Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.
research Integration of Ethylene and Auxin Signaling and the Developmental Consequences of Their Crosstalk
Ethylene and auxin hormones interact in complex ways that are essential for plant growth and development.
research Control of Hair Follicle Cell Fate by Underlying Mesenchyme Through a CSL–Wnt5a–FoxN1 Regulatory Axis
Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
research dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration
Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
research A Practical Guide for the Study of Human and Murine Sebaceous Glands In Situ
The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.
research Spironolactone: An Anti-Androgenic and Anti-Hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19
Spironolactone might help protect against severe lung problems in COVID-19 patients.
research Targeting Host Cell Proteases as a Potential Treatment Strategy to Limit the Spread of SARS-CoV-2 in the Respiratory Tract
Blocking enzymes that help the virus enter cells could be a promising way to treat COVID-19.
research Emerging Treatments in Alopecia
New alopecia treatments aim for better results and fewer side effects.
research IL-36α Promoted Wound-Induced Hair Follicle Neogenesis via Hair Follicle Stem/Progenitor Cell Proliferation
IL-36α helps grow new hair follicles and speeds up wound healing.
research Comparative Study on Seasonal Hair Follicle Cycling by Analysis of the Transcriptomes from Cashmere and Milk Goats
Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.
research Immune Niches for Hair Follicle Development and Homeostasis
Immune cells are crucial for hair growth and preventing hair loss.
research A Comprehensive Review of Biochemical Factors in Herbs and Their Constituent Compounds in Experimental Studies on Alopecia
Herbs might help with hair loss, but more research is needed to confirm their safety and effectiveness.
research Alopecia
The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
research Single-Cell Transcriptomics Reveals the Molecular Anatomy of Sheep Hair Follicle Heterogeneity and Wool Curvature
The research identified genes that explain why some sheep have curly wool and others have straight wool.
research Platelet-Rich Plasma in the Treatment of Alopecia Areata: A Review
Platelet-Rich Plasma (PRP) could potentially help regrow hair in people with Alopecia Areata, but more research is needed to confirm its effectiveness.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research The Transcriptional Landscape of Seasonal Coat Color Moult in the Snowshoe Hare
Researchers found genes that control hair color and growth change before the visible coat color changes in snowshoe hares.
research A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression
The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
research DKK1 Mediated Inhibition of Wnt Signaling in Postnatal Mice Leads to Loss of TEC Progenitors and Thymic Degeneration
Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
research Group-ICA Model Order Highlights Patterns of Functional Brain Connectivity
Choosing the right model order in brain connectivity analysis can affect the detection of differences between healthy individuals and those with seasonal affective disorder.
research Identification of Transcriptional Targets of Wnt/β-Catenin Signaling in Dermal Papilla Cells of Human Scalp Hair Follicles: EP2 Is a Novel Transcriptional Target of Wnt3a
Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.