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Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

PRP injections may improve skin texture and wrinkles based on patient feedback, despite no significant changes seen by dermatologists.

Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

New genes found linked to balding, may help develop future treatments.

Premature hair graying in young men is linked to family history, obesity, and smoking.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Kids with alopecia areata may experience more stress but not necessarily feel more anxious or depressed than others.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Early balding men may have insulin resistance, but lifestyle changes can help.

Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.

Androgens may block hair growth signals, targeting this could treat hair loss.