research Blinding in Placebo-Controlled Trials
The conclusion suggests that the zinc lozenge study is valid despite imperfect blinding, as many participants could not correctly identify their lozenge type.
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research Ethical Principles for Everyone
The document concludes that more research is needed on the hepatitis B vaccine's side effects and the effectiveness of certain treatments for specific diseases.
research Drugs and Androgenetic Alopecia: What to Look Out For
Certain drugs can worsen hair loss in people prone to androgenetic alopecia.
research Cyclin-Dependent Kinase 4/6 Inhibitors and Dermatologic Adverse Events: Results from the EADV Task Force Dermatology for Cancer Patients International Study
Skin side effects from CDK4/6 inhibitors in breast cancer patients are generally mild and treatable, allowing most patients to continue treatment.
research Spironolactone Use Does Not Increase the Risk of Female Breast Cancer Recurrence: A Retrospective Analysis
Taking spironolactone doesn't increase the chance of breast cancer coming back.
research Histological and Immunohistochemical Examination of the Effect of the Nonsteroidal Antiandrogen Flutamide on Some Organs of the Male Reproductive System in Albino Rats
Flutamide caused damage to male rat reproductive organs and may affect fertility.
research Early Inductive Events in Ectodermal Appendage Morphogenesis
Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
research Aromatase Inhibitors Induce Male Pattern Hair Loss in Women
Aromatase inhibitors cause male pattern hair loss in women.
research 17β-Estradiol Inhibits the Production of RANTES in Human Keratinocytes
17β-estradiol can reduce inflammation in the skin.
research Polymorphisms in Androgen and Estrogen Receptor Genes: Effects on Male Aging
Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.
research Atherogenesis: Estrogen Induction of Polysialylated NCAM Blocks Monocyte Capture by Vascular Endothelial Cells
Estrogen helps prevent artery plaque by stopping monocyte capture in blood vessels.
research In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach
Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.
research Biology of Estrogens in Skin: Implications for Skin Aging
Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
research The Role of Nuclear Hormone Receptors in Cutaneous Wound Repair
Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
research Androgenic Modulation of Arterial Baroreceptor Dysfunction and Neuroinflammation in Endotoxic Male Rats
Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.
research New Approaches to the Treatment of Osteoporosis
Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Blocking testosterone speeds up wound healing in males.
research Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An In Silico and In Vitro Study
Five preservatives may disrupt hormone function and need more health and environmental risk assessment.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Lowering testosterone speeds up wound healing in male mice.
research Estrogen Modulates Mesenchymal-Epidermal Interactions in the Adult Nipple
Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
research CAG Repeat Testing of Androgen Receptor Polymorphism: Is This Necessary for the Best Clinical Management of Hypogonadism?
Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.
research The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications
Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
research Improving Selective Androgen Receptor Modulator Discovery and Preclinical Evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching Is an Integrated Measure of Receptor Function
Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.
research Chapter 17: Selective Androgen Receptor Modulators (SARMs)
Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
research Cutaneous Malignant Melanoma Incidences Analyzed Worldwide by Skin Type Over Advancing Age of Males and Females: Evidence Estrogen and Androgenic Hair Are Risk Factors
Estrogen and androgenic hair increase melanoma risk, especially in European-ancestry individuals.
research Deletion of DNA Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D
Removing part of the vitamin D receptor stops vitamin D from working properly.
research Vitamin D Receptor: Molecular Signaling and Actions of Nutritional Ligands in Disease Prevention
Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.
research Hormone Replacement Therapy and the Skin
Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.
research Skin Connective Tissue and Aging
Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.