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Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Spironolactone most effective for hirsutism, but has side effects.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Women with hyperandrogenic amenorrhea have similar bone density to healthy women but lower than androgenized women without amenorrhea, and high DHEAS levels might affect bone density.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

Women with mild acne are more likely to have polycystic ovary syndrome (PCOS) than those without acne.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.