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Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Metformin is less effective in men with early-onset hair loss.

A girl with lupus and trisomy X has a higher risk of bone problems like avascular necrosis and osteoporosis.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

A pineal tumor caused a boy's early puberty, which changed from peripheral to central after treatment.

Cord blood platelets may have promising future medical uses but need more research.

A woman's severe male hormone excess was caused by a small, hard-to-find ovarian tumor.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

Myo-inositol plus α-lactalbumin works better than myo-inositol alone for improving symptoms of PCOS.

Tamoxifen effectively treats gynecomastia without causing impotence.

Testosterone with or without finasteride doesn't improve thinking skills in older men with low testosterone.

The conclusion is that lifestyle changes and weight loss are first-line treatments for infertility due to anovulation, with various medications and assisted reproductive technologies as additional options.

Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.

Acne is an important sign of androgen excess disorders in women.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Adrenal gland disease is common in ferrets and causes hair loss and other symptoms.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

A woman with acne and baldness was found to have a rare ovarian condition but successfully had a child through fertility treatment.

The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).

Inclusive and affirming healthcare is essential for improving transgender individuals' quality of life and health.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

DHT may increase the risk of heart disease and death in elderly men.