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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Human hair keratin might be good for filtering out harmful substances from water.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.

Peptide-based hydrogels are promising for healing chronic wounds effectively.

Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.

Ozone reacts more with unwashed hair, producing compounds due to scalp oils, which could lower ozone exposure but increase exposure to reaction products.

Optimized film improves finasteride skin absorption and treatment efficiency.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Coconut oil effectively treats sore gums from new dentures and is safe, affordable, and heals quickly.

Dupilumab treatment reduces Th2-related markers and helps hair growth in alopecia areata, showing Th2's role in the condition.

Different parts of the body have unique immune characteristics in their skin.

Girls had higher stress hormone levels during school due to social and emotional issues, while boys had higher overall hormone levels with slight changes when school started.

Alopecia areata patients show increased inflammation and OX40 activation, suggesting a new treatment target.

Adipose stem cell-derived exosomes are safe and effective for hair regrowth in AGA patients.

Blocking DPP4 can potentially speed up hair growth and regeneration, especially after injury or in cases of hair loss.

Chemical treatments and UV radiation severely damage the lipid layer on hair.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Women with androgenic alopecia are more likely to have polycystic ovaries and higher androgen levels, which may indicate PCOS.

Two drugs, ritlecitinib and brepocitinib, improved scalp hair loss condition markers.

Long-term use of Risperidone may be linked to a serious skin condition in bipolar patients, affecting their overall well-being.

Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.

Topical oxygen therapy may improve treatments for hair loss, acne, and chronic skin diseases with minimal side effects.

Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.

Herbal paste and oil extract might improve dog hair quality by retaining lipids.

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.