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research A Randomized Double-Blind Placebo-Controlled Pilot Trial on the Effects of Testosterone Undecanoate Plus Dutasteride or Placebo on Muscle Strength, Body Composition, and Metabolic Profile in Transmen
This study demonstrated that testosterone treatment increases muscle strength and alters body composition in transmen, and the addition of dutasteride does not impair these anabolic effects.
research Hirsutism
Hirsutism is abnormal male-pattern hair growth in females due to excess androgens.
research Character, Genre, and Ethos in Nineteenth-Century British Drama
This article discusses the perceived shortcomings of nineteenth-century British drama in addressing contemporary ideas, questioning its literary vitality beyond stage performance, and reports no new results.
research 115 EXOGENOUS TESTOSTERONE ALONE OR WITH FINASTERIDE INCREASES PHYSICAL PERFORMANCE, GRIP STRENGTH, AND LEAN BODY MASS IN OLDER MEN WITH LOW SERUM TESTOSTERONE
This study found that testosterone therapy improved physical performance, strength, lean body mass, and serum cholesterol in older men with low testosterone levels, with or without the addition of finasteride.
research Cognitive testing of a survey instrument for self-assessed menstrual cycle characteristics and androgen excess
This study presents a new survey instrument that was cognitively tested for understanding menstrual cycle characteristics and androgen excess, including hirsutism, alopecia, and acne.
research UJI STABILITAS FISIK FORMULASI SEDIAAN HAIR TONIC HERBAL BUAH MENTIMUN (Cucumis Sativus L) SEBAGAI PERAWATAN RAMBUT
In this study, researchers developed cucumber-based hair tonics and tested their physical stability, finding them to be homogenous and meet requirements for color and pH, suggesting potential use as a remedy for hair loss.
research Obesity, polycystic ovarian syndrome and thyroid dysfunction in women with epilepsy
This study found that women with epilepsy on carbamazepine and sodium valproate monotherapy experienced more significant weight gain but showed no difference in PCOS incidence compared to phenytoin users; elevated TSH levels were more common among those on sodium valproate.
research Are finasteride-related penile curvature/Peyronie’s disease Adverse Event Reports worthy of further clinical investigation? Disproportionality analysis based on both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) pharmacovigilance databases
This pharmacovigilance study found strong disproportionality signals suggesting an association between finasteride and Peyronie's disease-related clinical features, but the evidence does not confirm a causal link.
research Polycystic ovary syndrome is associated with weight‐loss attempts and perception of overweight independent of BMI: a population‐based cohort study
This study found that women with PCOS were more likely than women without PCOS to have multiple weight-loss attempts and perceive themselves as overweight, regardless of their actual obesity status.
research Relationship Between Steroid Hormones and Metabolic Profile in Women With Polycystic Ovary Syndrome
This study found that among women with polycystic ovary syndrome, higher levels of the hormones estrone and free testosterone were associated with an increased cardiometabolic risk, especially in those who were overweight or obese.
research Systemic Inflammatory Biomarkers in Alopecia Areata: The Role of SII, SIRI, and CRP/Albumin Ratio
This study found that patients with alopecia areata had significantly higher systemic immune-inflammation index levels compared to healthy controls, regardless of the disease's severity.
research Physical attractiveness, same-sex stimuli, and male venture capitalists’ financial risk-taking
In this study, researchers found that venture capitalists with below-average physical attractiveness are more influenced by the attractiveness of entrepreneurs when making investment decisions, and this sensitivity changes between investment rounds.
research The influence of obesity on Androstenedione to Testosterone ratio in women with polycystic ovary syndrome (PCOS) and hyperandrogenemia
This study found that obesity in PCOS women with biochemical hyperandrogenemia lowers androstenedione levels and increases the testosterone to androstenedione ratio, but this was not observed in women with clinical hyperandrogenemia or in controls.
research Positive Jacquet's sign in traction alopecia
This article is a letter to the editor discussing positive Jacquet's sign in traction alopecia and provides no new research results.
research Development of the Alopecia Areata Patient Priority Outcomes Instrument: A Qualitative Study
This study developed the Alopecia Areata Patient Priority Outcome (AAPPO), a new tool designed to measure and capture the symptoms and impacts of alopecia areata that matter most to patients.
research Quality of life measurement in alopecia areata. Position statement of the European Academy of Dermatology and Venereology Task Force on Quality of Life and Patient Oriented Outcomes
This review highlights current knowledge about quality of life assessment in alopecia areata, noting limited use of existing instruments and a need for further validation.
research 396 A novel investigator global assessment score for the evaluation of keratosis pilaris
In this study, the KPAI and KP-IGA scoring systems for assessing keratosis pilaris showed excellent interrater and intrarater reliability, offering standardized measures for clinical and research use.
research P-055 MONOZYGOTIC TRANSGENDER MALE TWINS: A CASE REPORT HIGHLIGHTING GENETIC CONCORDANCE IN GENDER DYSPHORIA
This study of monozygotic transgender male twins observed that consistent hormone therapy led to physical changes such as deepening voice and increased facial/body hair, with no reported mood-related adverse effects.
research Hirsutism scoring in polycystic ovary syndrome: concordance between clinicians' and patients' self-scoring
In this study, patients with polycystic ovary syndrome self-reported higher hirsutism scores compared to clinician assessments, but only clinician scores correlated with biochemical markers of hyperandrogenism.
research SAT645 Cardiac Autonomic Modulation In Transgender Men Under Gender-affirming Hormone Therapy
In this study, researchers found that transgender men exhibited impaired autonomic modulation during sympathetic stimulation compared to cisgender women, potentially due to testosterone treatment affecting cardiac autonomic modulation.
research Assessment of ultrasonographic features of polycystic ovaries is associated with modest levels of inter-observer agreement
This study found moderate to poor agreement among observers assessing ultrasonographic features of polycystic ovaries, suggesting the need for standardized training modules to improve consistency.
research 494 Epidermolysis bullosa pruriginosa, muscular dystrophy, and immune-mediated myasthenia gravis in a patient with homozygous nonsense PLEC mutation
This case study reports that a 26-year-old woman with epidermolysis bullosa prurogompsa also presented with unique findings of co-existing muscular dystrophy and immune-based myasthenia gravis, with significant improvement following steroid treatment.
research BH15 The burden of alopecia areata: examining baseline health-related quality of life and clinical assessment tools
This study found that alopecia areata significantly impacts patients' quality of life irrespective of hair loss severity, and concluded that the newer assessment tools AAPPO and AASIS better capture this impact compared to the traditional SALT measure.
research A Case-controlled Comparative Hospital-based Study on the Clinical, Biochemical, Hormonal, and Gynecological Parameters in Polycystic Ovary Syndrome
This study found that women with polycystic ovary syndrome in South India had higher body mass index, waist/hip ratio, and elevated levels of several hormones compared to controls, and waist/hip ratio may be a better risk indicator than body mass index.
research Testosterone levels in healthy men and the relation to behavioural and physical characteristics: facts and constructs
This review discusses the complex relationship between testosterone levels and male appearance and behavior, emphasizing the limitations and potential biases in making generalizations from current data.
research Use of rotary echoes in 2 H magic-angle spinning NMR for the quantitative study of molecular dynamics
This study demonstrated that a metric based on rotational echo intensity in 2H magic-angle spinning NMR can derive kinetic information for conformational exchange without complex modelling, achieving activation barriers consistent with prior findings.
research Matrix effects and application of matrix effect factor
This commentary discusses the challenges of matrix effects in LC–MS analysis and introduces the concept of a matrix effect factor using stable isotopically labeled internal standards to improve analysis reliability.
research A failure to relax.
This case study describes a 31-year-old man with myotonia and a history of hypertrophic cardiomyopathy and androgenic alopecia, who presented with arm and leg weakness.
research Parry–Romberg Syndrome: Radioclinical Dissociation in a Paucisymptomatic Form and a Proposed Diagnostic Framework
In this case report, a 38-year-old woman with Parry–Romberg syndrome displayed left-sided facial atrophy and subclinical central nervous system involvement detectable by neuroimaging, suggesting that even symptom-free cases may benefit from systematic brain evaluations.