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In this study, hydrophilic EG7 PTK-UR foams promoted better wound healing and tissue integration in a porcine model compared to more hydrophobic PTK-UR variants and a polyester-based alternative, while matching a collagen-based standard.

This abstract details known indications, categories, and potential reactions for various drugs, including anorexiants, estrogens, NSAID analgesics, cardiac glycosides, and migraine preventives, without reporting new clinical results.

This study found that biodegradable hyperbranched polyesters improved the solubility and loading capacity of hydrophobic drugs, with complete pyrene release achieved in 16 days under enzymatic conditions.

This study found that minoxidil is bioactivated through sulfation by the phenol-sulfating form of phenol sulfotransferase in human liver.

A woman developed a scalp condition from using minoxidil, which improved with a different treatment but left scarring.

This study reported the preparation of stable oil-in-water nanoemulsions that effectively incorporate ceramide-like molecules and minoxidil, suggesting these formulations may enhance distribution and availability of hydrophobic compounds in cosmetic applications.

Using minoxidil can cause severe skin reactions in some people.

This study found that using elastic nano-liposomes to deliver palmitoylethanolamide improved its transdermal delivery and enhanced its skincare effects, with minimal cytotoxicity and no allergic reactions observed.

In this study, researchers introduced a visible-light-mediated intramolecular cycloaddition method that selectively forms 6-azabicyclo[3.1.1]heptanes, suggesting these structures could offer promising new scaffolds for drug discovery and medicinal chemistry.

This study reports the preparation of a key intermediate for finasteride and epristeride with a 69% overall yield from pregnenolone acetate.

This study reported that reconstructed skin models can be useful for studying the effects of non-water-soluble topical products on xenobiotic metabolism, particularly in enzyme activities like EROD and GST.

This study found that nanoemulsions containing oleic acid or eucalyptol significantly enhanced the skin penetration of caffeine and naproxen compared to aqueous solutions, primarily by increasing solute diffusivity in the stratum corneum.

This article discusses the history and terminology of toxic epidermal necrolysis but reports no new clinical results.

This article reviewed the preparation, application, and characterization of ethosomes as drug delivery transporters and reported that in a double-blind randomized clinical study, ethosomal acyclovir significantly improved all evaluated parameters in skin delivery, highlighting potential for novel therapies.

This review discusses ethosomal delivery systems for topical drugs, highlighting their potential to improve treatment efficacy for conditions like herpes labialis and male pattern baldness, and reports no new clinical results.

This study reported that meloxicam-loaded spanlastics, created using the ethanol injection method, demonstrated potential as a drug delivery system with sustained release and effective entrapment efficiency.

A woman got a scalp condition from using latanoprost, but it improved after stopping the drug and starting other treatments.

This study describes the first known case of erosive pustular dermatosis of the scalp triggered by a burn from hair bleaching, which resolved completely with superpotent topical corticosteroids.

This study investigated multiple alkaline oxidative dehairing systems and found a consistent reaction mechanism for disulfide cleavage across systems, enhancing hair solubilization by enabling structural swelling and water uptake.

This chapter covers various dermatological drugs, cosmetics, and topical agents, focusing on the properties and uses of propolis, but does not present new clinical findings.

This study found that non-toxic polycarboxylic acids can achieve satisfactory hair perming effects with limited strength loss, suggesting they have potential as a safer alternative to harmful perming chemicals.

This study observed that PCE-DP may improve skin pigmentation by increasing epidermal turnover and inhibiting melanin uptake and inflammation in human epidermal keratinocytes.

This research found that liposome drug delivery systems, particularly with targeted modifications, show promise for improving effectiveness and reducing toxicity in combination cancer therapies.

Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.

This study introduced hydrogel microneedles loaded with palladium nanoparticles, which utilize the inherent cytotoxicity of polyethyleneimine to enhance the effectiveness of doxorubicin in treating melanoma, achieving a tumor inhibition rate of up to 98% in a murine model.

This study reported the development of new pyrazole-based MPC inhibitors that effectively inhibit mitochondrial pyruvate transport, showing potential as therapeutic candidates for conditions like metabolic dysfunction-associated steatohepatitis without activating PPARγ.

This paper discusses ethosomal drug delivery systems, highlighting their improved ability to enhance skin penetration and increase therapeutic effectiveness in treatments like acyclovir for herpes labialis and minoxidil for androgenic alopecia compared to standard formulations.