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Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.

Cyclosporin doesn't stop hair loss.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

New treatments targeting specific genes show promise for treating keratin disorders.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.

To diagnose hair loss, use a systematic approach including history, exams, and tests.

Trichoscopy is a useful non-invasive method for diagnosing different hair loss conditions.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

The document concludes that various clinical methods are used to assess ageing skin and the effectiveness of anti-ageing products.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Dermatoscopy is a useful tool for diagnosing hair disorders and can help choose samples for more detailed analysis.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

High-frequency ultrasonography is a useful but underused tool in dermatology for assessing skin cancers, monitoring diseases, and evaluating treatments.

Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.

Vitiligo causes white skin patches and is linked to autoimmune issues.