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This study found that selective inactivation of ribonucleotide excision repair in mouse epidermis led to spontaneous DNA damage, skin inflammation, and the development of squamous cell carcinoma, suggesting potential implications for cancer development in humans.

This study presents the first reported case of a collision tumor consisting of basal cell carcinoma and cutaneous leiomyosarcoma, emphasizing the need for pathologists to recognize such combinations.

This study identified interactions between EGF signaling and the GLI proteins in basal cell carcinoma that may contribute to the limited metastasis seen in this skin cancer.

This study suggests that keratoacanthomas may be distinguished from squamous cell carcinoma by identifying hair follicle structures, based on keratin expression and histological features observed in tumor samples.

This study found no significant differences in phosphatide distribution between normal and cancerous mouse epidermis during different stages of growth, despite variations in total phosphatide levels.

This study found that nevoid basal cell carcinomas originate in the epidermis and the upper part of the hair follicle, showing similarities to nonnevoid basal cell carcinomas.

This preliminary study suggests that Raman micro-spectroscopy can help differentiate basal cell carcinoma from hair follicles in skin tissue sections, although some misclassification of hair follicles as carcinoma was observed.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

This study found that squamous cell carcinomas from hair follicle stem cells are more prone to epithelial to mesenchymal transition and metastasis than those from interfollicular epidermis, due to distinct chromatin landscapes.

In this study, researchers found that deleting TNFα in PKCε transgenic mice reduced the development of cutaneous squamous cell carcinomas induced by UV radiation or a chemical protocol.

In this study, basal cell carcinoma developed in Ptch-deficient mice only after chemical treatment, not skin wounding, suggesting a second unknown event is necessary for tumor formation.

In this study, animal model observations suggested that GLI1 expression may reduce cSCC initiation but is not involved in the tumor's aggressiveness.

This study found that deleting the transcription factor Twist1 in keratinocytes significantly reduced UVB-induced skin carcinogenesis in mice, suggesting a potential target for preventing cutaneous squamous cell carcinoma.

This study found that LSD1 is crucial for embryonic skin barrier formation in mice, revealing its significant role in epidermal development and suggesting its potential as a target in skin diseases with barrier defects.

This study found that acute UVB exposure in mice increases the synthesis of retinoic acid in the epidermis, which is necessary for normal repair from UVB light.

This study found that nevoid basal cell carcinomas originate in the epidermis and upper hair follicles, resembling early nonnevoid basal cell carcinoma proliferations.

This study found that K15 is a useful marker for investigating the role of stem cells in canine hair follicle tumours, while nestin is not optimal.

This study found that GLI2 plays a key role in activating follistatin, an activin/BMP antagonist, in response to hedgehog signaling in human epidermal cells, with implications for hair follicle development and basal cell carcinoma.

In this study, researchers reported that specific immunoreactivity patterns observed in hair follicle stem cell markers suggest different origins for trichilemmoma, basal cell carcinoma, and squamous cell carcinoma in human skin tissues.

This study observed that the vitamin D receptor is crucial for hair follicle formation and altering tumor development in the Wnt signaling pathway, suggesting therapeutic potential for vitamin D analogues in related tumors.

The vitamin D receptor helps control hair growth and may protect against certain skin tumors.

Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.

This study found that benign tumors with a high risk of malignant progression primarily arise from hair follicle cells when a mutant ras gene is expressed in a specific population of epidermal cells in mice.

This study observed that benign skin tumors were more common than malignant ones, with squamous cell carcinoma being the most frequent type among malignant tumors.

This case report describes a 78-year-old male with adenocarcinoma and Hypertrichosis lanuginosa acquisita, highlighting the need to consider malignancy in patients with unexplained excessive hair growth.

This educational activity reports no new research findings; it aims to help physicians assess and improve their clinical skills through self-evaluation and continued medical education.

This study found that androgen receptor expression varied across different types of skin appendage tumors, with specific expression patterns noted in sebaceous and sweat gland tumors but absent in hair follicle tumors.

This study developed a novel multi-scale image descriptor using dictionaries for classifying histological images, achieving average recall and precision measures of 0.81 and 0.86 in identifying specific skin structures and pathologies.

This study found that new rabbit antisera against recombinant mouse involucrin effectively marked keratinocyte differentiation, with comparable expression patterns to human involucrin.

Understanding where cancer cells come from helps create better prevention and treatment methods.