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Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

A certain medication improved severe itching in a boy with liver and bowel disease by reducing histamine levels, suggesting a new treatment target.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

The yeast Pityrosporum ovale can cause skin allergies and infections, and antifungal treatments like ketoconazole are effective against it.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

A special hydrogel helps heal skin without scars and regrows hair.

The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

PPAR-γ may be a key target for treating alopecia areata and other skin conditions.

A young man had a rare case of hair cysts on his elbows, which was hard to diagnose and treat.

New gene mutations linked to skin conditions were found, bacteria and chemicals may worsen acne, a dog mutation could exist in humans, virus-like elements might be involved in psoriasis, and a vitamin D3 treatment doesn't prevent chemotherapy-related hair loss.

Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

The document concludes that dandruff and seborrheic dermatitis are linked to inflammation and skin changes, and treating them with specific shampoos can reduce these issues.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Wnt signaling is crucial for skin wound healing and reducing scars.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Hydrogels could lead to better treatments for wound healing without scars.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.

Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.

Plasmacytoid dendritic cells are a key factor in causing hair loss in alopecia areata and could help differentiate it from other hair loss conditions.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.