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The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.

A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.

The conclusion is that a combination of noninvasive treatments and lifestyle changes can improve skin health during menopause.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Treating melasma in men is difficult, especially for the deeper skin layers, and may need more than just topical treatments.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Testosterone therapy can help improve sexual function, mood, and bone density in women with low androgen levels, but more research is needed on long-term safety.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Melatonin solution helps treat hair loss in men and women.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.