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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Without keratin 10, there's more growth and development of oil-producing skin cells.

High doses of TCB cause severe health issues in marmoset monkeys.

Autophagy is crucial for normal sebaceous gland function and sebum composition.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

JAK inhibitors for alopecia areata are linked to minor side effects like headache and acne, but not to an increased risk of serious adverse events.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.

Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

A 38-year-old man was diagnosed late with Kearns-Sayre syndrome after being wrongly treated for epilepsy.

Oxidative stress is higher in women with PCOS, especially if they're obese, and it may increase their risk of heart disease.

Cinnamon can help manage symptoms of polycystic ovary syndrome, improve menstrual cycles and fertility, and positively affect cholesterol and blood sugar levels, but more research is needed to confirm these effects and find the best dosage.

Finasteride may help treat kidney disease caused by a high-fat diet by reducing harmful toxins and improving gut bacteria.

Menstrual abnormalities in PCOS women may not greatly affect their metabolic and hormonal profile.

Endovascular repair and open surgery for abdominal aortic aneurysms both result in a temporary decline in physical health, with no significant mental health difference, and a return to near normal health in 90 days.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Isotretinoin may cause temporary, reversible facial hair growth in some women.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

Hormonal imbalances, not insulin resistance or dyslipidemia, may be more important in causing acne in women over 25.

Skin changes can indicate starvation and nutritional deficiencies in anorexia nervosa.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Early diagnosis and treatment are key to managing health risks in teens with PCOS.