6 citations
,
January 2011 in “European Journal of Dermatology” This article discusses monilethrix, a rare human hair dysplasia caused by mutations in hair keratins, but reports no new clinical findings.
61 citations
,
June 2018 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that light stimulation of intrinsically photosensitive retinal ganglion cells in the eyes can activate hair follicle stem cells through a neural circuit involving the sympathetic nervous system.
16 citations
,
May 2015 in “Tissue Engineering Part C-methods” This study found that expanding hair follicle keratinocytes with a fibroblast feeder followed by short-term coculture with dermal papilla cells could restore their ability to form new hair follicles.
This study found that a combination of four transcription factors can transform mouse fibroblasts into cells resembling inner ear hair cells, potentially aiding research into hearing loss treatments.
68 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.
In this review, researchers analyzed literature on trichotillomania and found advances in understanding its neurobiology—highlighting dysregulated reward circuits and genetics—and treatments, with behavioral therapy and innovative pharmacological approaches improving outcomes where traditional SSRIs do not.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study explores a novel hypothesis for Male Pattern Baldness, suggesting that chronic tension in the scalp's Galea Aponeurotica creates a hypoxic environment affecting hair follicles, and proposes a Triad Therapeutic Protocol to address this underlying cause rather than just the symptoms.
3 citations
,
February 2009 in “Chinese Journal of Traumatology (english Edition)” This study found that implanting microencapsulated dermal papilla cells in rat ears led to hair follicle regeneration, suggesting a potential alternative to fresh isolated dermal papillae for inducing hair growth.
35 citations
,
September 2003 in “Archives of dermatology” This study proposed that the tiger tail phenomenon in trichothiodystrophy hair is caused by regular undulations of hair fibers, altering the optical properties seen under polarized light.
December 2025 in “Progress in Biomedical Engineering” This article reviews emerging mechanobiological strategies like electrical stimulation and microneedling combined with nanotechnology as non-invasive methods for hair loss treatment, suggesting these approaches could provide futuristic alternatives to current therapies such as minoxidil, finasteride, and hair transplants.
72 citations
,
October 2009 in “The FASEB journal” This study found that thyrotropin-releasing hormone (TRH) acts as a potent stimulator of hair growth in human scalp hair follicles, promoting elongation and prolonging the anagen phase.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study elucidates a mechanism for male pattern baldness involving chronic scalp tension leading to follicular hypoxia, rather than purely hormonal factors, and proposes a treatment targeting electrolyte, vascular, and neurological factors to restore balance.
January 2019 in “Institutional Repositories DataBase (IRDB)” This study developed in vitro methods to regenerate hair follicles and erector muscles by mimicking their native structures and mechanical conditions, reconstructing hair follicle-like structures and forming muscle-like tissues.
December 1991 in “Annals of the New York Academy of Sciences”
94 citations
,
February 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” This study concluded that epidermal growth factor may induce a 'catagen-like' phase in human hair follicles by disrupting normal cellular proliferation and migration patterns.
2 citations
,
July 2016 in “Journal of nature and science” This study found that human hair shafts emit electromagnetic signals that can create images through thin glass barriers, potentially influenced by static electricity.
January 2019 in “Institutional Repositories DataBase (IRDB)” This study achieved regeneration of hair follicle-like structures and erector muscle of hair in vitro by simulating cellular organization and applying mechanical stimuli.
2 citations
,
July 1994 in “Journal of Dermatological Science” This study found that a laboratory model using nude mice can produce human hair follicles with amino acid compositions resembling both normal and trichothiodystrophy-affected human scalp hair over extended periods.
January 2026 in “Surgical & Cosmetic Dermatology”
8 citations
,
January 2017 in “Methods in molecular biology” This article describes a protocol for using bioengineered techniques to regenerate functional hair follicles and their stem cell niches by manipulating epithelial and mesenchymal cells.
January 2026 in “SSRN Electronic Journal”
11 citations
,
October 2017 in “Journal of Investigative Dermatology” This study found that topical application of mitochondrial electron transport chain inhibitors stimulated hair follicle stem cell activation and hair regrowth in aged mice by promoting lactate production.
1 citations
,
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that modulating epithelial and mesenchymal cell interactions in vitro enabled nearly 100% efficient induction of hair follicles, suggesting potential applications for understanding and testing hair growth and graying.
42 citations
,
July 1993 in “Journal of Investigative Dermatology”
131 citations
,
July 2009 in “Experimental Dermatology” This review discusses the development and advances in studying trichogenic dermal cells for hair follicle morphogenesis, summarizing methods, bioassays, and molecular markers, but reports no new research findings.
September 2021 in “Kazanskij medicinskij žurnal” This article discusses the novel approach of introducing dissolved keratin into the body to enhance hair growth and reports no clinical results; further studies are needed to evaluate its efficacy.
1 citations
,
June 2016 in “Medicina” This article reviews monilethrix, a rare genetic hair disorder causing brittle hair and alopecia, and emphasizes the need for clinical diagnosis and characteristic tricoscopic findings.
33 citations
,
December 1982 in “Developmental Medicine & Child Neurology” The authors reviewed cases of six children with both hair-shaft abnormalities and neurological disorders, noting that such hair defects may indicate neurological conditions, including potentially treatable metabolic errors.
April 2025 in “International Journal For Multidisciplinary Research” This study explores hypertrichosis, a condition of excessive hair growth, highlighting its classification, diagnostic methods, and potential treatments. The authors emphasize the importance of individualized approaches and further genetic research to enhance treatment options for this primarily cosmetic issue that can signal systemic diseases.
125 citations
,
August 1992 in “Development” This study found that implanting isolated adult rat dermal papillae into ear cuts led to the emergence of unusually large vibrissa-type hair follicles, demonstrating their capacity to induce specific hair fiber characteristics.