Pathophysiology and Therapeutic Remodeling of Androgenetic Alopecia via Bio-Electric and Hydrodynamic Restoration

This paper challenges the current approach to treating Androgenetic Alopecia (Male Pattern Baldness) by highlighting the role of Galeal Tension-Induced Follicular Hypoxia as a key mechanism. It argues that chronic tension in the Galea Aponeurotica, caused by cranial muscle contraction, compresses perifollicular capillaries, leading to a hypoxic environment. This hypoxia triggers upregulation of HIF-1alpha, which increases TGF-beta1 and 5-alpha-reductase, contributing to hair loss as an ischemic event rather than a purely hormonal one. The authors propose a Triad Therapeutic Protocol that addresses the Electrolyte Medium, Vascular Dynamics, and Neurological Signal to restore balance and potentially reverse hair loss.