April 2017 in “The Journal of urology/The journal of urology” This study observed that both dutasteride and finasteride affected penile morphology in normotensive and hypertensive rats, with more pronounced changes in hypertensive animals, especially when treated with dutasteride.
April 2017 in “The Journal of urology/The journal of urology” This study found that Sonic Hedgehog protein treatment enhanced the sprouting and regeneration of pelvic ganglia and cavernous nerves after injury, with localization of delivery affecting outcomes.
25 citations
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November 2005 in “PubMed” This study found that finasteride altered androgen receptor expression in the rat epididymis without affecting the morphology of epididymal epithelium, suggesting a change in hormonal status.
May 2024 in “Reactions weekly”
36 citations
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September 2001 in “Journal of The European Academy of Dermatology and Venereology” This study found that sexual and erectile function in men taking finasteride 1 mg did not significantly differ from age-matched controls, suggesting sexual side effects may be less common than previously reported.
January 2025 in “Clinical and Experimental Optometry” This study found that men with androgenetic alopecia had significantly higher rates of dry eye symptoms and meibomian gland dysfunction compared to healthy controls, suggesting a potential link between the condition and these ocular issues.
November 2003 in “PubMed”
12 citations
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December 2013 in “The Journal of Urology” Men's age, urinary symptoms, and heart health risks create different types of erectile dysfunction.
October 2021 in “European urology open science”
1 citations
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January 2014 In this study, the release rate of Finasteride from Eudragit matrix tablets was found to be significantly influenced by the drug/Eudragit ratio and polymer viscosity, with formulation F9 being the most effective.
463 citations
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September 2004 in “Clinics in dermatology” This review discusses the development, function, and complex roles of sebaceous glands in acne and suggests future acne treatments should target inflammation and lipid production; it reports no new clinical results.
9 citations
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March 2021 in “Hormones” This review discusses how COVID-19 may affect gonadal function and potential gender differences, but reports no clinical results; it highlights possible mechanisms and new treatment approaches from recent literature.
34 citations
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September 2013 in “Urology” Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.
May 2003 in “Reactions Weekly”
January 2025 in “The World Journal of Men s Health” In this study, autologous intratesticular PRP injection was found to be a feasible and well-tolerated procedure with low complication rates and quick recovery, but the authors indicated that current evidence is insufficient to confirm its effectiveness for mTESE.
5 citations
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October 2018 in “Sains Malaysiana” This study found that testosterone administration reduced the expression of uterine receptivity molecules in ovariectomized rats, which may negatively affect early pregnancy establishment and female fertility.
21 citations
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November 2010 in “Talanta” This study reported the development of a novel and reliable liquid chromatographic method to measure testosterone and epitestosterone in human urine, offering sensitive detection for doping control.
13 citations
,
December 2020 in “Dermatologic Therapy” This review discusses the embryology, structure, and function of sebaceous glands and their involvement in skin disorders but reports no novel findings.
Using data from the FDA's adverse event reporting system, this study identified 59 drugs linked to reduced male semen quality, with finasteride, dutasteride, and tamsulosin among the most frequently reported.
12 citations
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March 2023 in “The FASEB Journal” This study found that platelet-rich plasma treatment significantly improved erectile function and restored neural structures in aged rats with erectile dysfunction, suggesting potential benefits for geriatric patients.
5 citations
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September 2024 in “Stem Cell Research & Therapy” This study found that stem cell transplantation effectively reduced acute inflammation-induced testicular damage, suggesting potential for cell-based therapies in addressing male infertility.
January 2024 in “Wiadomości Lekarskie” This study found that using a combined LH and FSH stimulation protocol significantly increased clinical pregnancy rates in women with low ovarian reserve compared to the standard protocol.
April 2015 in “The FASEB Journal” In this study, perinatal androgen deprivation in male rats led to elevated estrogen levels and a lack of sexual motivation towards gonadally-intact female rats.
January 2025 in “Indian Journal of Animal Research” This study observed that herbal feed supplementation in Frieswal breeding bulls improved semen volume and motility, while significantly lowering dihydrotestosterone levels, suggesting a potential mechanism for enhancing semen quality.
1 citations
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March 2025 in “Medical Molecular Morphology” This review discusses how androgens, commonly known for male reproductive roles, also influence the physiology and pathology of the human endometrium, though their exact roles in this tissue remain controversial and not fully understood.
July 1998 in “Chromatographia” Women with effluvium have higher levels of certain urinary steroids, possibly due to stress and increased adrenal activity.
2 citations
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September 2017 in “Archives of Medical Science” The researchers reported that finasteride treatment in male rats may lead to changes in antioxidant enzyme activity in their offspring's epididymis, potentially affecting sperm maturation.
September 2018 in “Translational Andrology and Urology” This study found that finasteride was associated with increased erectile dysfunction in men with benign prostatic hyperplasia, but this association was not statistically significant in those with male androgenic alopecia.
December 2016 in “The journal of sexual medicine” This study found that 63.8% of patients with lower urinary tract symptoms due to benign prostatic hyperplasia were undiagnosed with erectile dysfunction, and a significant majority responded positively to treatment.
July 2025 in “International Journal of Health and Medicine” In this study, dual therapy with tamsulosin and solifenacin significantly improved urinary symptom severity and bladder capacity in BPH patients, but did not alter post-void residual urine volume. This supports using the combination therapy for managing LUTS, especially for storage-related symptoms, in clinical settings.