Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This source discusses the aim of the Australian Journal of General Practice to deliver evidence-based information to help Australian general practitioners provide optimal patient care. Results from specific studies are not included.

This article discusses various causes and prevention methods for male pattern baldness but reports no new research findings.

The document concludes that current hair loss treatments have limitations and suggests researching new treatments targeting different factors of hair loss.

This study found that combining D-004 with finasteride results in more significant prevention of testosterone-induced prostate enlargement in rats compared to using either treatment alone.

This review discusses treatments for female sexual dysfunction in postmenopausal women, noting that the effectiveness of current pharmaceutical options is inconclusive and emphasizing the importance of individualized care.

In this study on mouse preputial glands, suppressing ATG7-dependent autophagy delayed age-related changes, affected lipid metabolism, and reduced pheromone production, highlighting autophagy's roles in glandular homeostasis and cell breakdown.

This study observed that equine epididymis mainly expresses the type 1 isoform of 5α-reductase and effectively converts progesterone and testosterone to DHP and DHT, while finasteride and dutasteride inhibited this activity.

This study on adult male rats found that finasteride treatment led to molecular changes linked to erectile dysfunction, while withdrawal from the drug did not alter these parameters.

This study found that patients using finasteride were up to twice as likely to experience sexual dysfunction, including ejaculation disorder, decreased libido, and impotence, compared to those not using the drug.

This review describes the surgical and nonsurgical genital rejuvenation options for addressing hair, morphology, and vascular changes, noting increased interest but providing no new clinical findings.

This study found that variations in Kv1 channel gene expression in the electric organ of Sternopygus correlate with sex differences and individual variations in their electric communication signals.

This study reviewed the pharmacological properties of fesoterodine and found that its ability to effectively treat overactive bladder, especially in the elderly, is likely due to its specific properties, including its receptor affinity, blood-brain barrier penetration, metabolic conversion, and extended-release formulation.

This study reviews current systemic treatments for hidradenitis suppurativa, highlighting traditional methods and new options like biological agents, and suggests that pharmacological therapies show promise, particularly for non-advanced cases, despite the disease's complex etiology involving factors such as genetics and inflammation.

This article reviews the management of lower urinary tract symptoms, highlighting drug therapy advancements that have reduced the frequency of surgical interventions.

This study found that epitestosterone acts as a weak antiandrogen by inhibiting receptor binding and 5α-reductase activity in animal models.

This study found that a single 2 ml injection of TEEV every 4 weeks offers similar beneficial effects with fewer side effects compared to injecting the same dose every 2 weeks in postmenopausal women.

This study concluded that male patients with improved lower urinary tract symptoms may have a lower risk of death, suggesting a potential benefit of treating symptoms beyond just managing patient discomfort.

This review discusses the impact of 5α-reductase inhibitors on sexual function and presents results from a meta-analysis of randomized controlled trials, without reporting new clinical findings.

This study found that finasteride may affect Ca 2+ signalling in human sperm by interacting with the PGE 1 -binding site, but its impact on fertilization requires further investigation.

This article reviews various studies in adult urology, covering topics like urinary incontinence risk and testosterone supplementation, but does not report new research findings.

In this cohort study of young Danish men, self-reported older age at voice break was linked to certain reproductive hormone changes that suggest reduced male fecundity, but associations with semen characteristics and testicular volume were not statistically significant.

This review discusses various alternative treatments for androgenetic alopecia, including pharmacological, surgical, and herbal therapies, without presenting new clinical findings.

This review discusses various treatment options for androgenic alopecia, noting finasteride's greater efficacy in men and identifies ongoing research needs, particularly for therapies like laser and stem cells.

Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.

This study found no significant relationship between hormone levels and sexual function in young women with hirsutism compared to a control group.

This study found that bladder outlet obstruction's common complication, detrusor overactivity, tends to persist with medical therapy or watchful waiting but significantly decreases with surgical treatment, especially prostatectomy.

This study reports on biofeedback treatment for dysfunctional voiding in three adult cases, providing insights into this condition when diagnosed beyond childhood.

This study found that individuals with ectodermal dysplasias often have a reduced secretion rate of submandibular saliva and altered protein concentrations, suggesting routine salivary tests may be beneficial in this population.

This study revealed that deleting EZH2 in mesenchyme-derived cells of the female reproductive tract led to impaired uterine gland development and pregnancy loss in mice, highlighting EZH2's crucial role in fertility.